63762-70-9

Usage

InChI:InChI=1/C13H17NO2/c15-12-9-5-4-8-11(12)13(16)14-10-6-2-1-3-7-10/h4-5,8-10,15H,1-3,6-7H2,(H,14,16)

Upstream product

• 118-55-8 phenyl Salicylate 
• 108-91-8 cyclohexylamine 
• 3417-55-8 3-cyclohexyl-benzo[e][1,3]oxazine-2,4-dione 
• 245679-60-1 N-cyclohexyl-N-tert-butyl-2-nitrobenzamide 

Downstream Products

• 143000-17-3 3-Cyclohexyl-2-oxo-2-phenyl-2,3-dihydro-2λ⁵-benzo[e][1,3,2]oxazaphosphinin-4-one 
• 1321192-18-0 10-cyclohexyl-7-nitrodibenzo[b,f][1,4]oxazepin-11(10H)-one 
• 1369423-63-1 11-cyclohexyl-3-(tetrahydro-2H-pyran-2-yl)benzo[f]pyridazino[4,5-b][1,4]oxazepine-4,10(3H,11H)-dione 
• 102074-95-3 2-(2,3-dibromo-propoxy)-benzoic acid cyclohexylamide 
• 3417-55-8 3-cyclohexyl-benzo[e][1,3]oxazine-2,4-dione 
• 143000-09-3 3-Cyclohexyl-2-phenyl-2,3-dihydro-benzo[e][1,3,2]oxazaphosphinin-4-one 
• 63887-50-3 2-allyloxy-benzoic acid cyclohexylamide 

Relevant academic research and scientific papers

Acid-catalysed N-alkyl heterolysis of tertiary pyridinecarboxamides and benzamides under mild conditions

Tertiary pyridinecarboxamides 1-9 and related benzamides 10-18 bearing a tert-butyl substituent were found to undergo alkyl-nitrogen heterolysis under unusually mild conditions. Accordingly, the corresponding secondary amides 19-33 have been isolated in high yields as the sole reaction product. Through a kinetic study based on pH-rate profiles and activation parameters, we have shown that the alkyl-nitrogen fission involved an initial protonation of the amide group that would concern the oxygen atom.