637741-40-3

Upstream product

• 637740-85-3 2,6-dimethyl-3-iodo-6-(hydroxymethyl)-2-cyclohexen-1-one 
• 637741-38-9 4-iodo-1,3-dimethyl-2-oxo-cyclohex-3-enecarbaldehyde 
• 81465-44-3 3-Iodo-2,6-dimethyl-cyclohex-2-enone 
• 637741-39-0 (E)-3-(4-Iodo-1,3-dimethyl-2-oxo-cyclohex-3-enyl)-2-methyl-acrylic acid ethyl ester 

Downstream Products

• 637741-42-5 3-{4-[4-(4-methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid 3-carboxy-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-propyl ester 
• 637740-87-5 (1R,2S,3R)-1-[(4-methoxybenzyloxy)methyl]-2,3-bis(4-methoxybenzyloxy)-4-hydroxybutyl (2E)-2-methyl-3-[1,3-dimethyl-2-oxo-4-[(1E,3S,4R,5S)-1,3,5-trimethyl-4-(4-methoxybenzyloxy)-1-pentadecenyl]-3-cyclohexenyl]propenoate 
• 637741-41-4 (E)-3-{4-[(E)-(3S,4R,5S)-4-(4-Methoxy-benzyloxy)-1,3,5-trimethyl-pentadec-1-enyl]-1,3-dimethyl-2-oxo-cyclohex-3-enyl}-2-methyl-acrylic acid (1R,2R,3S)-2,3-bis-(4-methoxy-benzyloxy)-1-(4-methoxy-benzyloxymethyl)-4-oxo-butyl ester 
• 637740-86-4 (1R,2S,3R)-1-[(4-methoxybenzyloxy)methyl]-2,3-bis(4-methoxybenzyloxy)-4-(tert-butyldimethylsiloxy)butyl (2E)-2-methyl-3-(1,3-dimethyl-2-oxo-4-iodo-3-cyclohexenyl)propenoate 

Relevant academic research and scientific papers

Chemistry and biology of khafrefungin. Large-scale synthesis, design, and structure-activity relationship of khafrefungin, an antifungal agent

Large-scale synthesis, design, and structure-activity relationships of khafrefungin are reported. Khafrefungin is an antifungal agent that inhibits inositol phosphorylceramide (IPC) synthase, a enzyme involved in fungal sphingolipid biosynthesis. Unlike o