Dihydrocyclosporin D is a chemical compound and a derivative of Cyclosporin A, which is a well-known immunosuppressant drug. It belongs to the family of natural products called cyclosporins. This non-polar, cyclic, polypeptide compound is believed to have a role in suppressing the immune system, similar to other cyclosporins. The term "dihydro" in its name refers to the additional hydrogen features in its structure, distinguishing it from cyclosporin D.

63775-91-7

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Basic information
1. Product Name: dihydrocyclosporin D
2. Synonyms: dihydrocyclosporin D;2-Val-dihydrocyclosporin;2-Valyl-dihydrocyclosporin;Cyclosporin A, 6-((3R,4R)-3-hydroxy-N,4-dimethyl-L-2-aminooctanoic acid)-7-L-alanine-;Cyclosporin A, 6-((R-(R*,R*))-3-hydroxy-N,4-dimethyl-L-2-aminooctanoic acid)-7-L-valine-;Cyclosporin, dihydro-2-valine-;Dihydrocyclosporin, Val(2)-
3. CAS NO:63775-91-7
4. Molecular Formula: C63H115N11O12
5. Molecular Weight: 1218.6537
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 1286.4°C at 760 mmHg
3. Flash Point: 731.8°C
4. Appearance: /
5. Density: 1.011g/cm³
6. Vapor Pressure: 0mmHg at 25°C
7. Refractive Index: 1.465
8. Storage Temp.: N/A
9. Solubility: N/A
10. CAS DataBase Reference: dihydrocyclosporin D(CAS DataBase Reference)
11. NIST Chemistry Reference: dihydrocyclosporin D(63775-91-7)
12. EPA Substance Registry System: dihydrocyclosporin D(63775-91-7)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 63775-91-7(Hazardous Substances Data)

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Uses

Used in Pharmaceutical Industry:
Dihydrocyclosporin D is used as an immunosuppressant for [application reason], which is to prevent the body from rejecting organ and bone marrow transplants. Its potent immunosuppressive activity makes it a potential candidate for use in this field.
Used in Research Applications:
Dihydrocyclosporin D is used as a research compound for [application reason], to study its immunosuppressive properties and potential applications in various medical fields. The limited scientific information about this dihydro derivative makes it an interesting subject for further investigation and exploration of its potential benefits and side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 63775-91-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,7,7 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63775-91:
(7*6)+(6*3)+(5*7)+(4*7)+(3*5)+(2*9)+(1*1)=157
157 % 10 = 7
So 63775-91-7 is a valid CAS Registry Number.

InChI:InChI=1/C63H115N11O12/c1-26-27-28-41(16)53(76)52-57(80)67-49(38(10)11)61(84)68(19)33-48(75)69(20)44(29-34(2)3)56(79)66-50(39(12)13)62(85)70(21)45(30-35(4)5)55(78)64-42(17)54(77)65-43(18)58(81)71(22)46(31-36(6)7)59(82)72(23)47(32-37(8)9)60(83)73(24)51(40(14)15)63(86)74(52)25/h34-47,49-53,76H,26-33H2,1-25H3,(H,64,78)(H,65,77)(H,66,79)(H,67,80)/t41-,42+,43-,44+,45+,46-,47+,49+,50+,51+,52?,53-/m1/s1

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