Basic information

Product Name: Cyclosporin B
Synonyms: CYCLOSPORIN B;Ala2-cyclosporine;Antibiotic S 7481F2;Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-alanyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Ala-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclosporine IMpurity-B;7-L-Alaninecyclosporine A;Cyclosporin B (9CI)
CAS NO:63775-95-1
Molecular Formula: C61H109N11O12
Molecular Weight: 1188.58
EINECS: N/A
Product Categories: Intermediates & Fine Chemicals;Peptides;Pharmaceuticals
Mol File: 63775-95-1.mol

Chemical Properties

Melting Point: 149-152°C
Boiling Point: 1289.7°C at 760 mmHg
Flash Point: 733.8°C
Appearance: Amorphous white solid
Density: 1.019g/cm³
Vapor Pressure: 0mmHg at 25°C
Refractive Index: 1.468
Storage Temp.: -20°C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
PKA: 13.32±0.70(Predicted)
CAS DataBase Reference: Cyclosporin B(CAS DataBase Reference)
NIST Chemistry Reference: Cyclosporin B(63775-95-1)
EPA Substance Registry System: Cyclosporin B(63775-95-1)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 63775-95-1(Hazardous Substances Data)

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SDS
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63775-95-1 Usage

Uses

Used in Organ Transplantation:
Cyclosporin B is used as an immunosuppressant in the medical field, particularly for revolutionizing organ transplantation. It plays a crucial role in the prevention of graft rejection, ensuring the success of transplant procedures.
Used in Pharmaceutical Applications:
Cyclosporin B is utilized as a group of nonpolar cyclic oligopeptides with immunosuppressant activity. This makes it a valuable compound for the development of new drugs and therapies in the pharmaceutical industry, targeting various immune-related conditions and diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 63775-95-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,7,7 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 63775-95:
(7*6)+(6*3)+(5*7)+(4*7)+(3*5)+(2*9)+(1*5)=161
161 % 10 = 1
So 63775-95-1 is a valid CAS Registry Number.

InChI:InChI=1/C61H109N11O12/c1-25-26-27-39(14)51(74)50-55(78)64-41(16)56(79)66(18)32-47(73)67(19)43(28-33(2)3)54(77)65-48(37(10)11)60(83)68(20)44(29-34(4)5)53(76)62-40(15)52(75)63-42(17)57(80)69(21)45(30-35(6)7)58(81)70(22)46(31-36(8)9)59(82)71(23)49(38(12)13)61(84)72(50)24/h25-26,33-46,48-51,74H,27-32H2,1-24H3,(H,62,76)(H,63,75)(H,64,78)(H,65,77)/b26-25+/t39?,40-,41+,42+,43+,44+,45+,46+,48+,49+,50-,51?/m1/s1

63775-95-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name	Cyclosporin B

1.2 Other means of identification

Product number	-
Other names	Antibiotic S 7481F2

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63775-95-1 SDS

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