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(4alpha,8beta,12xi)-12,13-epoxytrichothec-9-ene-4,8,15-triol, also known as deoxynivalenol or DON, is a type B trichothecene mycotoxin produced by various species of Fusarium fungi. It is commonly found in cereal crops such as wheat, barley, and maize, and can contaminate food products made from these grains. Deoxynivalenol is known to have toxic effects on humans and animals, particularly on the immune system, gastrointestinal tract, and reproductive system. It has been linked to causing vomiting, diarrhea, and other gastrointestinal issues, as well as potential long-term health effects.

63783-99-3

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63783-99-3 Usage

Uses

Used in Agricultural Industry:
Deoxynivalenol is used as a natural contaminant in the agricultural industry, affecting the quality and safety of cereal crops such as wheat, barley, and maize. The presence of DON in these crops can lead to economic losses and pose health risks to consumers.
Used in Food Safety and Regulation:
Deoxynivalenol is used as a reference substance in the development of methods and standards for the detection, monitoring, and regulation of mycotoxins in the food industry. Efforts are made to regulate and limit the levels of deoxynivalenol in food products to ensure consumer safety and reduce the risk of health issues associated with its consumption.
Used in Research and Development:
Deoxynivalenol is used as a subject of study in research and development, particularly in the fields of mycotoxin detection, food safety, and toxicology. Understanding the properties, effects, and mechanisms of action of DON can contribute to the development of strategies for its control and mitigation in the food supply chain.
Used in Public Health and Risk Assessment:
Deoxynivalenol is used as a factor in public health and risk assessment, as its presence in the food supply can pose significant health risks to humans and animals. Assessing the levels of DON in food products and understanding its toxicological effects can help inform guidelines and regulations to protect public health.

Check Digit Verification of cas no

The CAS Registry Mumber 63783-99-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,7,8 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 63783-99:
(7*6)+(6*3)+(5*7)+(4*8)+(3*3)+(2*9)+(1*9)=163
163 % 10 = 3
So 63783-99-3 is a valid CAS Registry Number.

63783-99-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Trichothec-9-ene-4,8,15-triol, 12,13-epoxy-, (4beta,8beta)-

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63783-99-3 SDS

63783-99-3Downstream Products

63783-99-3Relevant academic research and scientific papers

Antileukemic Compounds Derived from the Chemical Modification of Macrocyclic Trichothecenes. 1. Derivatives of Verrucarin A

Jarvis, Bruce B.,Stahly, G. Patrick,Pavanasasivam, Gowsala,Mazzola, Eugene P.

, p. 1054 - 1058 (2007/10/02)

Verrucarin A (2) was epoxidized to give the β-9,10-epoxide 7 (major product) and α-9,10-epoxide 9 (minor product).The β-epoxide 7 and its acetate 8 exhibit high in vivo antileukemic activity against P-388 mouse leukemia, whereas 2 and 9 are inactive.Epoxidation of verrucarin B (3) and roridin A (1) to their respective β-9,10-epoxides (11 and 12, respectively) also yields compounds with substantially increased activity.Allylic alcohols derived from 2, α-C8 (20), β-C8 (14), and C16 (15), were synthesized and tested; only 15 exhibited substantial in vivo activity.

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