638156-11-3 Usage
Description
CID-2011756 (638156-11-3) is a potent and selective ATP-competitive inhibitor of protein kinase D (PKD). IC50=3.2, 0.6 and 0.7 μM for PKD1, 2 and 3 respectively. Inhibits phorbol ester-induced PKD activation in LNCaP prostate cancer cells. Cell permeable.
Uses
This novel small molecule shows inhibitory activity against PKD1 which control various cellular processes and pathological conditions.
References
1) Sharlow et al. (2011), Discovery of diverse small molecule chemotypes with cell-based PKD1 inhibitory activity; PLoS One, 6 e25134
Check Digit Verification of cas no
The CAS Registry Mumber 638156-11-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,3,8,1,5 and 6 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 638156-11:
(8*6)+(7*3)+(6*8)+(5*1)+(4*5)+(3*6)+(2*1)+(1*1)=163
163 % 10 = 3
So 638156-11-3 is a valid CAS Registry Number.
