638188-40-6

Basic information

• Product Name: (-)-3-ethoxycarbonylamino-4-methyl-4-phenyl-oxazolidin-2-one
• Synonyms: (-)-3-ethoxycarbonylamino-4-methyl-4-phenyl-oxazolidin-2-one
• CAS NO: 638188-40-6
• Molecular Weight: 264.281
• Mol File: 638188-40-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (-)-3-ethoxycarbonylamino-4-methyl-4-phenyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-3-ethoxycarbonylamino-4-methyl-4-phenyl-oxazolidin-2-one(638188-40-6)
• EPA Substance Registry System: (-)-3-ethoxycarbonylamino-4-methyl-4-phenyl-oxazolidin-2-one(638188-40-6)

Safety Data

• Hazardous Substances Data: 638188-40-6(Hazardous Substances Data)

Upstream product

• 34713-70-7 2-Phenylpropanal 
• 1972-28-7 diethylazodicarboxylate 

Relevant articles and documents

The proline-catalyzed asymmetric amination of branched aldehydes

An efficient access to configurationally stable α,β- disubstituted α-amino aldehydes, oxazolidinones, and α-amino acids has been presented. Starting from simple and easily available racemic aldehydes, the α-aminated products were obtained using azodicarboxylates as the nitrogen source in up to 86 % ee and moderate to excellent yield. These products could further be converted both into the corresponding α-amino alcohols and, depending on the residue of the azodicarboxylates and the reaction conditions, into the oxazolidinones. On the other hand, oxidation towards the carboxylic acid and cleavage of the hydrazide bond under mild conditions revealed the free α-alkylated phenylglycine derivative. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.