63820-46-2Relevant articles and documents
Discovery of a Photoinduced Dark Catalytic Cycle Using in Situ LED-NMR Spectroscopy
Lehnherr, Dan,Ji, Yining,Neel, Andrew J.,Cohen, Ryan D.,Brunskill, Andrew P. J.,Yang, Junyu,Reibarkh, Mikhail
, p. 13843 - 13853 (2018)
We report the use of LED-NMR spectroscopy to study the reaction mechanism of a newly discovered photoinduced iron-catalyzed cycloisomerization of alkynols to cyclic enol ethers. By understanding on/off ligand binding to the catalyst, we were able to appro
Development and Proof of Concept for a Large-Scale Photoredox Additive-Free Minisci Reaction
Graham, Mark A.,Noonan, Gary,Cherryman, Janette H.,Douglas, James J.,Gonzalez, Miguel,Jackson, Lucinda V.,Leslie, Kevin,Liu, Zhi-Qing,McKinney, David,Munday, Rachel H.,Parsons, Chris D.,Whittaker, David T. E.,Zhang, En-Xuan,Zhang, Jun-Wang
, p. 57 - 67 (2021)
New route development activities toward ceralasertib (AZD6738) have resulted in the discovery of an efficient, acid additive-free, photoredox Minisci reaction. Mechanistic understanding resulting from LED-NMR reaction profiling, quantum yield measurements
Facile Quantum Yield Determination via NMR Actinometry
Ji, Yining,DiRocco, Daniel A.,Hong, Cynthia M.,Wismer, Michael K.,Reibarkh, Mikhail
supporting information, p. 2156 - 2159 (2018/04/30)
A simplified approach to quantum yield (φ) measurement using in situ LED NMR spectroscopy has been developed. The utility and performance of NMR actinometry has been demonstrated for the well-known chemical actinometers potassium ferrioxalate and o-nitrobenzaldehyde. A novel NMR-friendly actinometer, 2,4-dinitrobenzaldehyde, has been introduced for both 365 and 440 nm wavelengths. The method has been utilized successfully to measure the quantum yield of several recently published photochemical reactions.
