638207-71-3Relevant academic research and scientific papers
Synthesis and structural model of an α(2,6)-sialyl-T glycosylated MUC1 eicosapeptide under physiological conditions
Dziadek, Sebastian,Griesinger, Christian,Kunz, Horst,Reinscheid, Uwe M.
, p. 4981 - 4993 (2008/02/11)
To study the effect of O-glycosylation on the conformational propensities of a peptide backbone, a 20residue peptide (GSTAPPAHGVT-SAPDTRPAP) representing the full length tandem repeat sequence of the human mucin MUC1 and its analogue glycosylated with the
Biomimetic synthesis of the tumor-associated (2,3)-sialyl-T antigen and its incorporation into glycopeptide antigens from the mucins MUC1 and MUC4
Dziadek, Sebastian,Brocke, Constanze,Kunz, Horst
, p. 4150 - 4162 (2007/10/03)
Glycoproteins on epithelial tumor cells often exhibit aberrant glycosylation profiles. The incomplete formation of the glycan side chains resulting from a down-regulated glucosamine transfer and a premature sialylation results in additional peptide epitop
Synthetic Glycopeptides of the Tandem Repeat Sequence of the Epithelial Mucin MUC4 with Tumour-associated Carbohydrate Antigens
Brocke, Constanze,Kunz, Horst
, p. 2052 - 2056 (2007/10/03)
Glycohexadecapeptides representing the tandem repeat sequence of the epithelial mucin MUC4 were prepared by applying a solid-phase methodology. The required glycosyl amino acid building blocks containing the tumour-associated saccharide antigens TN/
