6383-60-4Relevant academic research and scientific papers
N-Tosylhydrazine-mediated deoxygenative hydrogenation of aldehydes and ketones catalyzed by Pd/C
Zhou, Lei,Liu, Zhenxing,Liu, Yizhou,Zhang, Yan,Wang, Jianbo
, p. 6083 - 6087 (2013)
A mild and efficient method for the deoxygenative hydrogenation of aldehydes and ketones has been developed. The reaction is mediated by N-tosylhydrazine with H2 (1 atm) as the reductant and 10% Pd/C as the catalyst.
Straightforward reductive esterification of carbonyl compounds with carboxylic acids through tosylhydrazone intermediates
Garcia-Munoz, Angel-Humberto,Tomas-Gamasa, Maria,Perez-Aguilar, M. Carmen,Cuevas-Yanez, Erick,Valdes, Carlos
scheme or table, p. 3925 - 3928 (2012/08/28)
The reaction of carboxylic acids with tosylhydrazones in basic media gives rise to the corresponding esters through an O-H insertion reaction in the in situ generated diazo compound. The process is operationally very simple, catalyst free, and very general with regard to the structure of both coupling partners. In particular, the esterification can be accomplished by employing tosylhydrazones derived from enolizable carbonyl compounds. Considering the ready availability of tosylhydrazones from carbonyl compounds, this reaction can be visualized as a reductive esterification of carbonyl compounds.
