638352-65-5

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-chloropyridin-4-yl)-2,5-dimethyl-1H-pyrrole is used as a key intermediate for the synthesis of biologically active compounds, contributing to the development of new drugs. Its unique chemical structure allows for the creation of molecules with potential therapeutic effects, targeting various medical conditions.
Used in Agrochemical Industry:
In the agrochemical industry, 1-(2-chloropyridin-4-yl)-2,5-dimethyl-1H-pyrrole is utilized as a building block for the synthesis of compounds with pesticidal, herbicidal, or fungicidal properties. Its incorporation into these compounds can enhance their effectiveness in protecting crops and managing pests.
Used in Organic Chemistry:
1-(2-chloropyridin-4-yl)-2,5-dimethyl-1H-pyrrole serves as an important intermediate in the synthesis of a wide range of organic compounds. Its versatile structure facilitates the development of novel molecules with various applications, including but not limited to materials science, chemical research, and the creation of new pharmaceutical agents.

Upstream product

• 14432-12-3 4-Amino-2-chloropyridine 
• 110-13-4 2,5-hexanedione 

Downstream Products

• 956384-73-9 4,6'-diamino-2,2'-bipyridine 
• 18511-69-8 4,4'-diamino-2,2'-bipyridyl 

Relevant academic research and scientific papers

Towards allosteric receptors synthesis of β-cyclodextrin- functionalised 2,2'-bipyridines and their metal complexes

Herein, we present three new 2,2'-bipyridines that carry two β-cyclodextrin moieties in different substitution patterns. When coordinated by zinc(II) or copper(I) ions (or their complexes), these compounds undergo conformational changes and switch between

Synthesis of diisothiocyanato-functionalized 2,2-bipyridines

Three new diisothiocyanato-functionalized 2,2-bipyridines have been synthesized in four consecutive steps. Starting from 4-amino-2-chloro- and 2-amino-6-bromopyridine, respectively, we first prepared the corresponding diamino-2,2-bipyridines via homo- or Negishi cross-coupling reactions which were subsequently reacted with thiophosgene.

Synthesis of Differently Disubstituted 2,2′-Bipyridines by a Modified Negishi Cross-Coupling Reaction

A general practical approach to a number of differently disubstituted 2,2′-bipyridines from substituted 2-bromo- and 2-chloropyridines by application of modified Negishi cross-coupling conditions has been developed. These 2,2′-bipyridines carry versatile functional groups that can be elaborated further, as demonstrated for some examples. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.