63845-28-3

Basic information

• Product Name: N-CBZ-4-PIPERIDINEACETIC ACID
• Synonyms: N-CBZ-4-PIPERIDINEACETIC ACID;1-N-CBZ-4-PIPERIDINEACETIC ACID;1-Cbz-4-Piperidineacetic acid;Cbz-1-piperidine-4-acetic acid;2-(1-((Benzyloxy)carbonyl)piperidin-4-yl)acetic acid;2-(1-phenylmethoxycarbonylpiperidin-4-yl)acetic acid
• CAS NO: 63845-28-3
• Molecular Formula: C₁₅H₁₉NO₄
• Molecular Weight: 277.32
• Product Categories: pharmacetical
• Mol File: 63845-28-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 460.1°C at 760 mmHg
• Flash Point: 232°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 2.93E-09mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: N-CBZ-4-PIPERIDINEACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-CBZ-4-PIPERIDINEACETIC ACID(63845-28-3)
• EPA Substance Registry System: N-CBZ-4-PIPERIDINEACETIC ACID(63845-28-3)

Safety Data

• Hazardous Substances Data: 63845-28-3(Hazardous Substances Data)

Usage

General Description

N-CBZ-4-piperidineacetic acid, also known as N-CBZ-4-piperidinecarboxylic acid, is a chemical compound with the molecular formula C14H19NO4. It is a piperidine derivative that contains a carbobenzyloxy (Cbz) protecting group on the nitrogen atom. N-CBZ-4-PIPERIDINEACETIC ACID is commonly used in organic synthesis as a building block for the preparation of various pharmaceuticals and bioactive molecules. It is known for its ability to act as a versatile intermediate in the synthesis of natural and unnatural compounds, making it a valuable reagent in chemical research and drug development. Additionally, N-CBZ-4-piperidineacetic acid exhibits potential medicinal properties, including analgesic and anti-inflammatory effects, making it a subject of interest in pharmaceutical research.

InChI:InChI=1/C15H19NO4/c17-14(18)10-12-6-8-16(9-7-12)15(19)20-11-13-4-2-1-3-5-13/h1-5,12H,6-11H2,(H,17,18)

Upstream product

• 501-53-1 benzyl chloroformate 
• 73415-84-6 2-(piperidin-4-yl)acetic acid hydrochloride 
• 51052-78-9 4-piperidinylacetic acid 

Downstream Products

• 168050-53-1 4-[({(S)-1-[(S)-3-Benzyloxy-2-(naphthalene-2-sulfonylamino)-propionyl]-pyrrolidin-2-ylmethyl}-carbamoyl)-methyl]-piperidine-1-carboxylic acid benzyl ester 
• 867162-98-9 4-({[(3-chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]-carbamoyl}-methyl)-piperidine-1-carboxylic acid benzyl ester 
• 1622247-27-1 1-[5-(benzyloxy)-1H-indol-3-yl]-2-(piperidin-4-yl)ethanone hydrochloride 
• 1622247-25-9 benzyl 4-[2-(5-(benzyloxy)-1H-indol-3-yl)-2-oxoethyl]piperidine-1-carboxylate 
• 1622247-26-0 1-[5-(benzyloxy)-1H-indol-3-yl]-2-(piperidin-4-yl)ethanone 

Relevant articles and documents

COMPOUNDS USEFUL AS CSF1 MODULATORS

This invention relates to novel compounds and to pharmaceutical compositions comprising the novel compounds. More specifically, the invention relates to compounds useful as Colony Stimulating Factor 1 Receptor (cFMS) modulators (e.g. cFMS inhibitors). This invention also relates to processes for preparing the compounds, uses of the compounds in treatment and methods of treatment employing the compounds. Specifically, the invention relates to the use of the compounds for the treatment of cancer and autoimmune diseases.

HETEROCYCLIC THROMBIN INHIBITORS

Heterocyclic thrombin inhibitors are provided which have the structure STR1 wherein n, R, R 1, R 2, R 3, G, G x, R. sup.6', Ra, Xa, R 6, Rb, R 3, p, Q, A and R 4 are as defined herein.