63845-28-3

Basic information

• Product Name: N-CBZ-4-PIPERIDINEACETIC ACID
• Synonyms: N-CBZ-4-PIPERIDINEACETIC ACID;1-N-CBZ-4-PIPERIDINEACETIC ACID;1-Cbz-4-Piperidineacetic acid;Cbz-1-piperidine-4-acetic acid;2-(1-((Benzyloxy)carbonyl)piperidin-4-yl)acetic acid;2-(1-phenylmethoxycarbonylpiperidin-4-yl)acetic acid
• CAS NO: 63845-28-3
• Molecular Formula: C₁₅H₁₉NO₄
• Molecular Weight: 277.32
• Product Categories: pharmacetical
• Mol File: 63845-28-3.mol

Chemical Properties

• Boiling Point: 460.1°C at 760 mmHg
• Flash Point: 232°C
• Appearance: /
• Density: 1.216g/cm³
• Vapor Pressure: 2.93E-09mmHg at 25°C
• Refractive Index: 1.552
• Storage Temp.: 2-8°C
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: N-CBZ-4-PIPERIDINEACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: N-CBZ-4-PIPERIDINEACETIC ACID(63845-28-3)
• EPA Substance Registry System: N-CBZ-4-PIPERIDINEACETIC ACID(63845-28-3)

Safety Data

• Hazardous Substances Data: 63845-28-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
N-CBZ-4-PIPERIDINEACETIC ACID is used as a building block for the synthesis of various pharmaceuticals and bioactive molecules. Its versatility as an intermediate allows for the creation of natural and unnatural compounds, contributing to the advancement of drug discovery and design.
Used in Organic Synthesis:
In the field of organic synthesis, N-CBZ-4-PIPERIDINEACETIC ACID is utilized as a valuable reagent. Its carbobenzyloxy protecting group on the nitrogen atom facilitates the synthesis of complex organic compounds, making it an essential component in the development of new chemical entities.
Used in Medicinal Chemistry:
N-CBZ-4-PIPERIDINEACETIC ACID is employed as a subject of interest in medicinal chemistry due to its potential medicinal properties. Its analgesic and anti-inflammatory effects are currently under investigation, with the aim of developing new therapeutic agents for pain management and inflammation control.

InChI:InChI=1/C15H19NO4/c17-14(18)10-12-6-8-16(9-7-12)15(19)20-11-13-4-2-1-3-5-13/h1-5,12H,6-11H2,(H,17,18)

Upstream product

• 501-53-1 benzyl chloroformate 
• 73415-84-6 2-(piperidin-4-yl)acetic acid hydrochloride 
• 51052-78-9 4-piperidinylacetic acid 

Downstream Products

• 867162-98-9 4-({[(3-chloro-pyrazin-2-yl)-(2-phenyl-quinolin-7-yl)-methyl]-carbamoyl}-methyl)-piperidine-1-carboxylic acid benzyl ester 
• 1622247-27-1 1-[5-(benzyloxy)-1H-indol-3-yl]-2-(piperidin-4-yl)ethanone hydrochloride 
• 1622247-25-9 benzyl 4-[2-(5-(benzyloxy)-1H-indol-3-yl)-2-oxoethyl]piperidine-1-carboxylate 
• 1622247-26-0 1-[5-(benzyloxy)-1H-indol-3-yl]-2-(piperidin-4-yl)ethanone 
• 168050-53-1 4-[({(S)-1-[(S)-3-Benzyloxy-2-(naphthalene-2-sulfonylamino)-propionyl]-pyrrolidin-2-ylmethyl}-carbamoyl)-methyl]-piperidine-1-carboxylic acid benzyl ester 

Relevant articles and documents

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