63847-47-2

Upstream product

• 3911-55-5 N-benzoyl-carbonimidic acid dichloride 
• 57668-48-1 N-benzoyl-morpholine-4-carboximidoyl chloride 
• 108221-21-2 Morpholine-4-carboxylic acid {morpholin-4-yl-[(E)-thiobenzoylimino]-methyl}-amide 
• 121314-60-1 4-Morpholino-6-phenyl-2H-1,3,5-oxadiazin-2-thion 
• 110-91-8 morpholine 
• 540-72-7 sodium thiocyanide 

Relevant academic research and scientific papers

Concerning the Synthesis and the Dimroth Rearrangement of 4-(Dialkylamino)-2H-1,3,5-oxadiazine-2-thiones

The title compounds 3 are readily obtained by reaction of N,N-dialkylchloroformamidines 2 with potassium thiocyanate.The amidines 2 can be prepared profitably from isocyanide dichlorides 1 with the aid of N-(trimethylsilyl)dialkylamines.The thiones 3 behave very sensitively towards acids and are rearranged completely to 4-(dialkylamino)-2H-1,3,5-thiadiazin-2-ones 4 by treatment with acetic acid.

REACTION OF N-ACYLTHIOUREAS WITH ELECTROPHILIC REAGENTS SYNTHESIS OF 1,3,5-OXADIAZINIUM SALTS, 1,2,4-DITHIAZOLIUM SALTS AND BENZOTHIAZOLES

N-Acylthioureas 1 can be easily transformed into 2,4-diamino-6-aryl-1,3,5-oxadiazinium salts 12, 2,4-diamino-6-aryl-1,3,5-thiadiazinium salts 13, 3-amino-5-aryl-1,2,4-dithiazolium salts 19 and 2-acylimino-benzothiazolines 22, respectively by reaction with