63857-40-9Relevant academic research and scientific papers
8-Aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins
-
, (2008/06/13)
This invention relates to 8-aza-9-oxo(and dioxo)-thia-11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly useful as renal vasodilators, for the prevention of thrombus formation, to induce growth hormone release, and as regulators of the immune response.
11,12-Secoprostaglandins. 4. 7-(N-alkylmethanesulfonamido)heptanoic acids
Jones,Holtz,Bicking,Cragoe Jr.
, p. 1299 - 1304 (2007/10/13)
A series of 7-(N-alkylmethanesulfonamido)heptanoic acids has been prepared which represents an extension of the 8-aza-11,12-secoprostaglandin studies. The compounds mimic the natural prostaglandins in that they markedly stimulate cAMP formation in the mouse ovary assay.
