63869-19-2

Basic information

• Product Name: decane-2,9-diaminium dichloride
• Synonyms: 2,9-decanediamine, hydrochloride (1:2); Decane-2,9-diamine dihydrochloride
• CAS NO: 63869-19-2
• Molecular Formula: C₁₀H₂₆Cl₂N₂
• Molecular Weight: 245.2328
• Mol File: 63869-19-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 250.2°C at 760 mmHg
• Flash Point: 127.1°C
• Vapor Pressure: 0.022mmHg at 25°C
• CAS DataBase Reference: decane-2,9-diaminium dichloride(CAS DataBase Reference)
• NIST Chemistry Reference: decane-2,9-diaminium dichloride(63869-19-2)
• EPA Substance Registry System: decane-2,9-diaminium dichloride(63869-19-2)

Safety Data

• Hazardous Substances Data: 63869-19-2(Hazardous Substances Data)

Upstream product

• 125763-76-0 [8-(tert-Butoxycarbonyl-methyl-amino)-octyl]-methyl-carbamic acid tert-butyl ester 

Relevant articles and documents

Polyamine analogues with antitumor activity

A series of tetraamines derived from 1,8-diaminooctane was prepared and tested as antitumor agents. The reaction of 1,8-diaminooctane with acrylonitrile gave N,N'-bis(cyanoethyl)-1,8-diaminooctane, which was reduced to tetraamine 20. Alkylation of the terminal nitrogen atoms of the tetra-Boc derivative of this compound by methyl or ethyl halide followed by removal of the Boc groups gave the bis(alkyl)polyamines 26a and 26b, respectively. These three compounds exhibit promising antitumor activity in the mouse L1210 leukemia model. Coadministration of a polyamine oxidase inhibitor potentiated the antitumor activity.