63891-88-3

Basic information

• Product Name: Ethyl 4-broMo-2,2-diMethylacetoacetate
• Synonyms: Ethyl 4-broMo-2,2-diMethylacetoacetate;ETHYL 4-BROMO-2,2-DIMETHYL-3-OXOBUTANOATE
• CAS NO: 63891-88-3
• Molecular Formula: C₈H₁₃BrO₃
• Molecular Weight: 237.09102
• Mol File: 63891-88-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Ethyl 4-broMo-2,2-diMethylacetoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Ethyl 4-broMo-2,2-diMethylacetoacetate(63891-88-3)
• EPA Substance Registry System: Ethyl 4-broMo-2,2-diMethylacetoacetate(63891-88-3)

Safety Data

• Hazardous Substances Data: 63891-88-3(Hazardous Substances Data)

Usage

Description

Ethyl 4-broMo-2,2-diMethylacetoacetate, also known as Ethyl 4-Bromo-2,2-Dimethyl-3-Oxobutanoate, is a chemical compound with a unique molecular structure that features a bromo group and a methyl group attached to a central acetoacetate core. Ethyl 4-broMo-2,2-diMethylacetoacetate has been identified for its potential applications in various fields due to its specific chemical properties.

Uses

Used in Pharmaceutical Industry:
Ethyl 4-broMo-2,2-diMethylacetoacetate is used as an IRAK4 inhibitor for treating a wide range of diseases, including inflammatory, autoimmune, cardiovascular, central nervous system, dermatology, bone, and ophthalmic conditions. Its application as an IRAK4 inhibitor helps in modulating the immune response and reducing inflammation, making it a promising candidate for therapeutic intervention in these diseases.
Additionally, Ethyl 4-broMo-2,2-diMethylacetoacetate has been found to be effective in cancer treatment. As an IRAK4 inhibitor, it can potentially disrupt the signaling pathways involved in cancer cell growth and proliferation, offering a new avenue for cancer therapy.

Upstream product

• 597-04-6 ethyl 2,2-dimethyl-3-oxobutanoate 

Downstream Products

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• 215529-48-9 tert-Butyl 2-[6-[3-[4-(diphenylmethoxy)piperidino]-propoxy]imidazo[1,2-b]pyridazin-2-yl]-2-methylpropionate 
• 215529-50-3 2-[6-[3-[4-(diphenylmethoxy)piperidino]-propoxy]imidazo[1,2-b]pyridazin-2-yl]-2-methylpropionic acid 
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• 698367-89-4 2-methyl-2-(1-trityl-1H-imidazol-4-yl)propionic acid ethyl ester 
• 64464-49-9 2-methyl-2-(1-triphenylmethyl-1H-imidazol-4-yl)propanal 

Relevant articles and documents

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