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639-15-6

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  • 3-[(1R,3R,5R,10S,13R,14S,17R)-1,3,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

    Cas No: 639-15-6

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639-15-6 Usage

Description

(1beta,3beta,5beta,8xi,9xi)-1,3,14-trihydroxycard-20(22)-enolide, also known as bufalin, is a naturally occurring steroid compound derived from the venom of the Chinese toad Bufo gargarizans. It has been traditionally used in Chinese medicine for its anti-inflammatory and anti-tumor properties. Bufalin possesses a unique molecular structure that allows it to interact with various biological targets, making it a promising candidate for therapeutic applications.

Uses

Used in Oncology:
Bufalin is used as an anti-cancer agent for its ability to inhibit the growth of various cancer cells, including breast, lung, and colon cancer. It achieves this by inducing apoptosis and inhibiting cell proliferation. Its potential anti-angiogenic and anti-metastatic effects also contribute to its anti-cancer properties.
Used in Cardiovascular Medicine:
Bufalin has been investigated for its potential cardioprotective effects in various heart diseases. Its ability to modulate cellular processes and protect the heart from damage makes it a candidate for further research in this field.
Used in Neurology:
Bufalin has also been studied for its neurological benefits in neurodegenerative conditions. Its potential to protect neurons and improve cognitive function highlights its possible use in the treatment of neurodegenerative diseases.
Further research is needed to fully understand the potential therapeutic applications of bufalin and to develop novel drug delivery systems to enhance its efficacy and bioavailability in various medical fields.

Check Digit Verification of cas no

The CAS Registry Mumber 639-15-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,3 and 9 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 639-15:
(5*6)+(4*3)+(3*9)+(2*1)+(1*5)=76
76 % 10 = 6
So 639-15-6 is a valid CAS Registry Number.

639-15-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(1R,3R,5R,10S,13R,14S,17R)-1,3,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

1.2 Other means of identification

Product number -
Other names Acovenosigenin A

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:639-15-6 SDS

639-15-6Upstream product

639-15-6Downstream Products

639-15-6Relevant articles and documents

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v. Euw,Reichstein

, p. 485,497 (1950)

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