63919-17-5

Basic information

• Product Name: platinum(2+) azanide benzylpropanedioic acid (1:2:1)
• CAS NO: 63919-17-5
• Molecular Formula: C₁₀H₁₄N₂O₄Pt
• Molecular Weight: 421.3132
• Mol File: 63919-17-5.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 378.4°C at 760 mmHg
• Flash Point: 196.8°C
• Vapor Pressure: 2.12E-06mmHg at 25°C
• CAS DataBase Reference: platinum(2+) azanide benzylpropanedioic acid (1:2:1)(CAS DataBase Reference)
• NIST Chemistry Reference: platinum(2+) azanide benzylpropanedioic acid (1:2:1)(63919-17-5)
• EPA Substance Registry System: platinum(2+) azanide benzylpropanedioic acid (1:2:1)(63919-17-5)

Safety Data

• Hazardous Substances Data: 63919-17-5(Hazardous Substances Data)

Usage

General Description

Platinum(2+) azanide benzylpropanedioic acid (1:2:1) is a chemical compound consisting of platinum(2+) cations, azanide anions, and benzylpropanedioic acid molecules in a 1:2:1 ratio. Platinum(2+) is a transition metal known for its use in catalytic reactions, while azanide is a type of nitrogen-containing ion. Benzylpropanedioic acid is a dicarboxylic acid with potential applications in the field of medicine and material science. This chemical compound could potentially have uses in catalytic reactions, pharmaceuticals, and materials science due to the unique combination of its components. Further research and testing may reveal its specific properties and potential applications.

Upstream product

• 7732-18-5 water 
• 616-75-1 2-benzylmalonic acid 

Relevant articles and documents

DNA binding studies of a series of cis-[Pt(Am)2X2] complexes (Am = inert amine, X = labile carboxylato ligand)

A series of platinum(II) complexes of formulae cis-[Pt(Am) 2X2] (where Am represents an inert amine and X a labile (carboxylato) ligand) have been prepared and characterized by elemental analysis, ESI-MS, IR and 1H NMR spectroscopy. The single-crystal molecular structures were determined for cis-[Pt(opea)(cbdca-2H)], cis-[Pt(hmpy)(cbdca-2H)], cis-[Pt(NH3)2(bzmal-2H)] and cis-[Pt(hmpy)(μ-dcch-2H)2] (where opea is picolylamine, hmpy represents 4-hydroxymethylpyridine, cbdca-2H, is 1,1-cyclobutanedicarboxylate anion, bzmal-2H stands for benzylmalonate anion and dcch-2H is trans-1,2-cyclohexanedicarboxylate anion). The interaction of all compounds with DNA was investigated with different techniques: viscosity measurements and emission fluorescence spectroscopy were used to investigate the changes induced by the binding of the platinum compounds to calf-thymus DNA, while atomic force microscopy and electrophoretic mobility allowed evaluating the potential alterations of pBR322 plasmid DNA. The cytotoxic behavior of the platinum compounds on human leukemia HL-60 tumor cell lines was also examined.

Synthesis and characterization of Pt(II) complexes with amine and carboxylato ligands. Crystal structure of (1,1-cyclobutanedicarboxylato)di(ethylamine)platinum(II)·H2O

Two methods for the synthesis of compounds of the type cis-PtA2X2 (A2 = bidentate amine or two monodentate amines and X2 = bidentate or two monodentate carboxylato ligands) were evaluated. The compounds were characterized by multinuclear NMR and IR spectroscopies. The 195PT NMR chemical shifts were in the range - 1615 to - 1976 ppm, the higher field values corresponding to the complexes containing bidentate ligands. The coupling constants 3J(195Pt-1H) are approximately 35 Hz, while the 2J(195Pt-1HN) are about 70 Hz. One coupling constant 2J(195Pt-13C) (53 Hz) was also measured. The crystal structure of the compound, cis-Pt(1,1-cyclobutanedicarboxylato)(C2H5NH2)2·H2O belongs to the P21/n space group with a=9.468(5), b =9.365(4), c = 16.473(7) A?, β = 105.08(3)°, Z = 4 and R1 = 0.0576. The Pt-N bond distances are 1.992(5) and 2.020(5) A?, while the Pt-O bonds are 2.000(4) and 2.015(4) A?. The molecules are held together by intermolecular H-bonds involving the lattice water molecules and the two free carbonyl O atoms and between the amino H atoms and the Pt-bonded C-O groups. (C) 2000 Elsevier Science S.A.