6392-25-2Relevant academic research and scientific papers
Design, synthesis and evaluate in vitroantifungal activity of novel benzamide derivatives
Wang, Xuesong,Tang, Xiaorong
, p. 549 - 554 (2019/09/18)
Summary: A series of novel benzamide derivatives according to fluopicolide were designed and synthesized following the rule of combination carboxylic acid amides and amines derivatives together. The antifungal activity of the 15 new compounds were evaluated in vitroagainst five pathogenic fungi, including Sclerotinia sclerotiorum,Gibberella zeae, Rhizoctonia solani, Helminthosporium maydisand Botrytis cinerea. Almost all the structure have not been reported, except compounds 3, 5and 6. A surprising finding is that all the five tested fungi breed faster than negative controls when supplementary with compound 7-15, respectively.
Process for preparing 5-aroyl-1,2-dihydro-3H-pyrrolo[1,2-A]pyrrole-1,1-dicarboxylates
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, (2008/06/13)
5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1,1-dicarboxylates of the formula STR1 are prepared from 2-halopyrroles. Hydrolysis and β-decarboxylation of these compounds affords ketorolac and related compounds.
Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
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, (2008/06/13)
An improved process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters and nitriles and for subsequent hydrolysis thereof is disclosed. In the improved process, an aroyl morpholide is reacted with the pyrrolo pyrrole system and the resultant decomposed with base.
