639495-67-3Relevant articles and documents
New styryl sulfones as anticancer agents
Vedula, Manohar Sharma,Pulipaka, Aravind Babu,Venna, Chandrasekhar,Chintakunta, Vamsee Krishna,Jinnapally, Sreenu,Kattuboina, Venkata Adiseshu,Vallakati, Ravi Krishna,Basetti, Vishnu,Akella, Venkateswarlu,Rajgopal, Sriram,Reka, Ajaya Kumar,Teepireddy, Sravan Kumar,Mamnoor, Prem Kumar,Rajagopalan, Ramanujam,Bulusu, Gopalakrishnan,Khandelwal, Akash,Upreti, Vijay V.,Mamidi, Srinivas Rao
, p. 811 - 824 (2007/10/03)
New styryl sulfone compounds have been synthesized and evaluated for their anti-proliferative activity. Among the compounds synthesized, one compound (7k) has shown 51% tumor growth inhibition in mice implanted with HT-29 human carcinoma at 400 mg kg-1 orally.