63955-01-1Relevant articles and documents
Hydrogenolysis of 1-Aminopyrazoles: Synthesis of Primary and Secondary Alkylamines
Adembri, G.,Camparini, A.,Ponticelli, F.,Scotton, M.
, p. 321 - 326 (2007/10/02)
The tautomerizable N-aminopyrazolone 9, the O-methyl 1 and N-methyl derivatives 4 were condensed with carbonyl compounds to give the alkenylaminopyrazoles 12, 2a-g and 5c, wich, under mild conditions, were hydrogenated to the corresponding alkylamino derivatives.The subesquent hydrogenation of the latter ones gave different results according to the structure of the starting material.The 5-methoxy-1-alkylaminopyrazoles 3a-g yielded the 5-methoxypyrazole 15 and the corresponding primary amines in good yields.On the contrary, N-methyl-1-alkylaminopyrazolone-5 6c gave 1-a lkylpyrazolone-3 8.
ON THE REACTIVITY OF SOME N-AMINO HETEROCYCLES TOWARDS DIAZOMETHANE
Ponticelli, Fabio,Tedeschi, Piero
, p. 1315 - 1320 (2007/10/02)
The occurrence of hydrogen bonding between the nitrogen atom of the NH2 group and a neighbouring enolic proton in tautomerizable N-amino heterocycles allows diazomethane methylation on the NH2 moiety.
1-Aminopyrazolin-5-ones. Synthesis and reactivity
Adembri, Giorgio,Camparini, Alfredo,Ponticelli, Fabio,Tedeschi, Piero
, p. 957 - 962 (2007/10/02)
A synthesis of 1-aminopyrazolin-5-ones (I) by chloramine attack on the 2-benzylpyrazolones (IV d-e) has been accomplished.Nucleophilic substitution reactions of aminopyrazolones (I) are investigated; with 1,4-diketones, N,N'-pyrrolylpyrazolones (XVIIa-c)
