63971-99-3

Basic information

• Product Name: ethyl 3-(1H-indol-3-yl)-2-nitropropanoate
• Synonyms: 1H-indole-3-propanoic acid, alpha-nitro-, ethyl ester; Ethyl 3-(1H-indol-3-yl)-2-nitropropanoate
• CAS NO: 63971-99-3
• Molecular Formula: C₁₃H₁₄N₂O₄
• Molecular Weight: 262.2613
• Mol File: 63971-99-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 451.9°C at 760 mmHg
• Flash Point: 227.1°C
• Density: 1.305g/cm³
• Vapor Pressure: 2.34E-08mmHg at 25°C
• Refractive Index: 1.611
• CAS DataBase Reference: ethyl 3-(1H-indol-3-yl)-2-nitropropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-(1H-indol-3-yl)-2-nitropropanoate(63971-99-3)
• EPA Substance Registry System: ethyl 3-(1H-indol-3-yl)-2-nitropropanoate(63971-99-3)

Safety Data

• Hazardous Substances Data: 63971-99-3(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 50-00-0 formaldehyd 
• 626-35-7 nitroacetic acid ethyl ester 
• 93020-17-8 diethyl (indol-3'-ylmethyl)nitromalonate 
• 87-52-5 3-(Dimethylaminomethyl)indole 
• 101427-38-7 2,2'-dinitro-2,2'-(2-aza-propanediyl)-di-malonic acid tetraethyl ester 
• 438053-07-7 ethyl 2-nitroacrylate 

Downstream Products

• 61-54-1 tryptamine 
• 6519-66-0 DL-tryptophan ethyl ester 
• 31731-23-4 3-(2-nitroethyl)indole 

Relevant articles and documents

An efficient one-pot reaction of indoles, nitroacetate, and paraformaldehyde for the synthesis of tryptophan derivatives

An efficient method for the synthesis of tryptophan analogues has been developed via one-pot reaction of commercial available indoles, ethyl nitroacetate, and paraformaldehyde in the presence of molecular sieves. The reaction provided tryptophan nitro-pre

Efficient preparation of 2-indolyl-1-nitroalkane derivatives employing nitroalkenes as versatile Michael acceptors: New practical linear approach to alkyl 9H-β-carboline-4-carboxylate

(Chemical Equation Presented) The combination of cerium(III) chloride heptahydrate and sodium iodide supported on silica gel is known to promote Michael-type additions. Continuing our work on solvent-free conditions, the CeCl3·7H2O-N