63974-05-0

Basic information

• Product Name: 2-Hexene-1,6-diol, (E)-
• CAS NO: 63974-05-0
• Molecular Formula: C6H12O2
• Molecular Weight: 116.16
• Mol File: 63974-05-0.mol

Chemical Properties

• CAS DataBase Reference: 2-Hexene-1,6-diol, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hexene-1,6-diol, (E)-(63974-05-0)
• EPA Substance Registry System: 2-Hexene-1,6-diol, (E)-(63974-05-0)

Safety Data

• Hazardous Substances Data: 63974-05-0(Hazardous Substances Data)

Usage

Uses

Used in Polymer Synthesis:
2-Hexene-1,6-diol, (E)is used as a key intermediate in the production of various polymers, including polyesters and polyurethanes, due to its ability to react with other monomers to form polymer chains.
Used in Cosmetics and Personal Care Products:
In the cosmetics and personal care industry, 2-Hexene-1,6-diol, (E)is used as a solvent, plasticizer, and emulsifying agent, contributing to the formulation of products with desired textures and properties.
Used in Pharmaceutical Formulations:
2-Hexene-1,6-diol, (E)is employed in the pharmaceutical industry as a solvent and plasticizer, aiding in the development of formulations with improved stability and efficacy.
Used as a Preservative:
Due to its antimicrobial properties, 2-Hexene-1,6-diol, (E)can be used as a preservative in certain formulations, helping to prevent the growth of microorganisms and extend the shelf life of products.
Overall, 2-Hexene-1,6-diol, (E)is a versatile chemical compound that plays a significant role in the production of numerous everyday items across various industries.

Upstream product

• 32114-34-4 hex-2-yne-1,6-diol 
• 27925-22-0 6,8-dioxa-bicyclo[3.2.1]oct-2-ene 
• 98897-64-4 (E)-6-[(tert-butyldimethylsilyl)oxy]-2-hexen-1-ol 
• 193948-52-6 (E)-ethyl 6-((tert-butyldimethylsilyl)oxy)hex-2-enoate 

Downstream Products

• 629-11-8 1,6-hexanediol 
• 63974-06-1 1,6-dichloro-hex-2t-ene 
• 821-41-0 5-Hexen-1-ol 
• 62319-56-6 5-trans,8-cis,11-cis,14-cis-eikosan-tetraensaeuremethylester 
• 63974-08-3 1-bromo-9-chloro-non-5t-en-2-yne 
• 63974-07-2 9-chloro-non-5t-en-2-yn-1-ol 
• 63998-64-1 1-chloro-nonadeca-4t,7c,10c,13c-tetraene 
• 63974-09-4 1-chloro-nonadec-4t-ene-7,10,13-triyne 
• 278783-10-1 (S)-2-vinyltetrahydrofuran 
• 278783-09-8 (R)-2-vinyltetrahydrofuran 
• 1072-60-2 2-vinyltetrahydrofuran 

Relevant articles and documents

A chiral bidentate sp2-N ligand, naph-diPIM: Application to CpRu-catalyzed asymmetric dehydrative C-, N-, and O-allylation

A handy new ligand: The CpRu complex (Cp=cyclopentadienyl) of a new type of chiral bisamidine ligand with a naphtho[1,2-b:7,8-b]dipyrroloimidazole (Naph-diPIM) skeleton with a Bronsted acid efficiently catalyzes dehydrative intermolecular C-allylation with high enantio- and regioselectivity. The catalytic system also gives nearly enantiomerically pure cycloalkanes and N- and O-heterocycles with a substrate/catalyst ratios of up to 10 000.

Cyclopropenium-activated cyclodehydration of diols

The dehydrative cyclization of diols to cyclic ethers via cyclopropenium activation is described. Using 2,3-diphenylcyclopropene and methanesulfonic anhydride, a series of 1,4-and 1,5-diols are rapidly cyclized to furnish tetrahydrofurans and tetrahydropyrans in high yield. Eleven total substrates are shown, including a gram scale cyclization of a diterpene derivative.

Asymmetrie dehydrative cyclization of ω-hydroxy allyl alcohols catalyzed by ruthenium complexes

New axially chiral ligands and their allyl esters have been designed and synthesized. The combination of these ligands with [CpRu(CH3CN)3]PF6 has realized highly efficient intramolecular dehydrative cylization of w-hydroxy allyl alcohols, to give a-alkeny

Reactions of 6,8-Dioxabicyclo(3.2.1)oct-3-ene and 6,8-Dioxabicyclo(3.2.1)oct-2-ene with Lithium Aluminium Hydride

Reduction of 6,8-dioxabicyclo(3.2.1)oct-3-ene (6) with lithium aluminium hydride in refluxing 1,2-dimethoxyethane gives 2-hydroxymethyl-3,4-dihydro-2H-pyran (7) in an excellent yield.However, under identical conditions 6,8-dioxabicyclo(3.2.1)oct-2-ene (8) gives a mixture of 4-hexen-1-ol (9), 5-hexen-1-ol (10) and 2-hexene-1,6-diol (11).When 6 is refluxed with LAH in di-n-propyl ether, 7 is obtained in addition to 2-hydroxymethyl-2,3-dihydro-6H-pyran (33).However, compound 8 remains unaffected by LAH under similar conditions.