64001-13-4Relevant academic research and scientific papers
N-Iodosuccinimide-Promoted [3 + 2] Annulation Reaction of Aryldiazonium Salts with Guanidines to Construct Aminotetrazoles
Yang, Yi-Lin,Li, Shen,Zhang, Fa-Guang,Ma, Jun-An
supporting information, p. 8894 - 8898 (2021/11/24)
A N-iodosuccinimide (NIS)-promoted [3 + 2] annulation reaction of aryldiazonium salts with guanidines has been developed for the construction of previously elusive 2-aryl-5-amino-2H-tetrazoles. This transformation takes advantage of readily available starting materials, proceeds under metal-free, mild, and robust conditions, and holds broad functional group compatibility. The utility of this protocol is further manifested via coupling, annulation, deamination, and denitrogenation derivatizations.
Synthesis of 2-aryl-2H-tetrazoles via a regioselective [3+2] cycloaddition reaction
Patouret, Remi,Kamenecka, Theodore M.
supporting information, p. 1597 - 1599 (2018/03/28)
A regioselective cycloaddition reaction of arenediazonium salts with trimethylsilyldiazomethane is reported. A series of 2-aryltetrazoles were obtained in good to moderate yields with wide functional group compatibility. Furthermore, this cycloaddition reaction opens the way to build up the versatile intermediate 2-aryl-5-bromotetrazole.
