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64013-54-3

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64013-54-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 64013-54-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,1 and 3 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 64013-54:
(7*6)+(6*4)+(5*0)+(4*1)+(3*3)+(2*5)+(1*4)=93
93 % 10 = 3
So 64013-54-3 is a valid CAS Registry Number.

64013-54-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[(2,6-dimethylphenoxy)methyl]-4-(2-methylphenyl)-1H-1,2,4-triazole-5-thione

1.2 Other means of identification

Product number -
Other names 5-(2,6-dimethyl-phenoxymethyl)-4-o-tolyl-2,4-dihydro-[1,2,4]triazole-3-thione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64013-54-3 SDS

64013-54-3Upstream product

64013-54-3Downstream Products

64013-54-3Relevant articles and documents

Anticonvulsant activity and selective inhibition of NAD dependent oxidations in rat brain homogenates by newer mercaptotriazoles

Parmar,Chaudhary,Chaudhary,Kumar,Spiro

, p. 971 - 975 (2007/10/09)

Eight 1-(2,6-dimethylphenoxyacetyl)-4-(substituted phenyl)thiosemicarbazides were cyclized to the corresponding 5-(2,6-dimethylphenoxymethyl)-4-(substituted phenyl)-3-mercapto-1,2,-4(4H)-triazoles and 5-(2,6-dimethylphenoxymethyl)-4-(substituted phenyl)-3-[1,2,4(4H)-triazolethioglycolic] acids. These compounds were characterized by their sharp melting points, elemental analyses, and IR spectra and were evaluated for anticonvulsant activity. The degree of protection (range) provided by these thiosemicarbazides, triazoles, and triazolethioglycolic acids at a dose of 100 mg/kg ip against pentylenetetrazol (90 mg/kg sc)-induced convulsions in mice was 10-50, 20-80, and 10-70%, respectively, where cyclization to triazoles increased anticonvulsant activity of the precursor thiosemicarbazides. Increased protection by these compounds against convulsions was generally associated with decreased 24-hr pentylenetetrazol-induced mortality. These compounds exhibited selective in vitro inhibition of nicotinamide adenine dinucleotide (NAD)-dependent oxidation of pyruvate, α-ketoglutarate, and NADH by rat brain homogenates while NAD-independent oxidation of succinate remained unaltered. The presence of added NAD to the reaction mixture during in vitro oxidation of pyruvic acid not only increased the respiratory activity of rat brain homogenates but also decreased the inhibitory effectiveness of thiosemicarbazides, triazoles, and triazolethioglycolic acids. The degree of selective inhibition of NAD-dependent oxidations was unrelated to their anticonvulsant activity.

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