64013-70-3 Usage
Uses
Kanamycin acid sulfate is the sulfate salt form of Kanamycin A, an antibiotic complex produced by Streptomyces kanamyceticus Okami & Umezawa from Japanese soil. Comprised of three components, kanamycin A, the major component, and kanamycins B and C, two minor congeners. Antibacterial.
Check Digit Verification of cas no
The CAS Registry Mumber 64013-70-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,1 and 3 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 64013-70:
(7*6)+(6*4)+(5*0)+(4*1)+(3*3)+(2*7)+(1*0)=93
93 % 10 = 3
So 64013-70-3 is a valid CAS Registry Number.
64013-70-3Relevant articles and documents
The last step of kanamycin biosynthesis: Unique deamination reaction catalyzed by the α-ketoglutarate-dependent nonheme iron dioxygenase KanJ and the NADPH-dependent reductase KanK
Sucipto, Hilda,Kudo, Fumitaka,Eguchi, Tadashi
supporting information; experimental part, p. 3428 - 3431 (2012/06/30)
Mystery solved: Using heterologous expression, the activities of two enzymes exclusively belonging to the kanamycin biosynthetic pathway have been identified in vitro. A distinctive reaction mechanism (see scheme) to produce kanamycin is proposed and the previously unknown catalytic deamination activity of KanJ dioxygenase is uncovered. Copyright
