64018-26-4Relevant academic research and scientific papers
Synthesis of 2H,2H-perfluoroalkyl and 2H-perfluoroalkenyl carboxylic acids and amides
Achilefu, Samuel,Mansuy, Laurence,Selve, Claude,Thiebaut, Sylvie
, p. 19 - 26 (2007/10/02)
An efficient and convenient procedure for the synthesis of 2-perfluoroalkyl ethanoic acids by direct oxidation of 2-perfluoroalkyl ethanols with Jones' reagent (CrO3/H2SO4) is described.Treatment of the acids with aqueous sodium hydroxide gave 3-perfluoroalkyl, 3-fluoro-2,3-propenyl carboxylic acids wich may be used for the preparation of the corresponding chlorides and amides. - Keywords: Synthesis; 2-Perfluoroalkyl ethanoic acids; Jones' reagent; NMR spectroscopy; IR spectroscopy
