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2-(4-aminophenyl)-2,4-dihydro-5-methyl-3H-pyrazol-3-one, commonly known as medazepam, is a synthetic benzodiazepine derivative characterized by its anxiolytic, sedative, and muscle relaxant properties. It exerts its effects by modulating the central nervous system, specifically by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA), leading to a calming influence on both the brain and the body.

6402-08-0

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6402-08-0 Usage

Uses

Used in Pharmaceutical Industry:
Medazepam is utilized as a therapeutic agent for the short-term management of anxiety disorders, insomnia, and muscle spasms. Its anxiolytic effects are attributed to its ability to increase the effects of GABA, providing a calming effect on the brain and promoting relaxation.
Used in Clinical Settings:
In clinical practice, medazepam is prescribed in tablet form for the temporary alleviation of symptoms associated with anxiety and insomnia. Due to its potential for dependence and the risk of withdrawal effects, its use is closely monitored, and it is typically recommended for short-term treatment only.
Used in Research and Development:
Medazepam serves as a valuable compound in the research and development of new pharmaceuticals targeting the GABAergic system. Its mechanism of action provides insights into the development of novel anxiolytic and sedative agents, potentially leading to the discovery of safer and more effective treatments for anxiety-related disorders and sleep disturbances.

Check Digit Verification of cas no

The CAS Registry Mumber 6402-08-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,4,0 and 2 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6402-08:
(6*6)+(5*4)+(4*0)+(3*2)+(2*0)+(1*8)=70
70 % 10 = 0
So 6402-08-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H11N3O/c1-7-6-10(14)13(12-7)9-4-2-8(11)3-5-9/h2-5H,6,11H2,1H3

6402-08-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-aminophenyl)-5-methyl-4H-pyrazol-3-one

1.2 Other means of identification

Product number -
Other names 2-(4-aminophenyl)-5-methyl-2,4-dihydro-3h-pyrazol-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6402-08-0 SDS

6402-08-0Upstream product

6402-08-0Downstream Products

6402-08-0Relevant academic research and scientific papers

DRUGS COMPRISING COMBINATION OF ANTITHROMBOTIC AGENT WITH PYRAZOLONE DERIVATIVE

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, (2008/06/13)

It is intended to provide drugs for treating and/or preventing ischemic diseases which are safe and have little side effects. Namely, drugs comprising a combination of an antithrombotic agent and a pyrazolone derivative defined in the description or its pharmaceutically acceptable salt.

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