6402-89-7

Basic information

• Product Name: disulfanilamide
• Synonyms: disulfanilamide;Sulphanyl acid N-(4-sulphamoylphenyl)amide
• CAS NO: 6402-89-7
• Molecular Formula: C₁₂H₁₃N₃O₄S₂
• Molecular Weight: 327.38
• Mol File: 6402-89-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 602.5°C at 760 mmHg
• Flash Point: 318.2°C
• Appearance: /
• Density: 1.528g/cm³
• Vapor Pressure: 1.81E-14mmHg at 25°C
• Refractive Index: 1.669
• CAS DataBase Reference: disulfanilamide(CAS DataBase Reference)
• NIST Chemistry Reference: disulfanilamide(6402-89-7)
• EPA Substance Registry System: disulfanilamide(6402-89-7)

Safety Data

• Hazardous Substances Data: 6402-89-7(Hazardous Substances Data)

Usage

General Description

Disulfanilamide is a chemical compound that belongs to the class of sulfonamides, which are known for their antibacterial properties. It is commonly used in the treatment of various bacterial infections, including urinary tract infections, respiratory infections, and skin infections. Disulfanilamide works by inhibiting the growth and proliferation of bacteria by interfering with their metabolic processes. It is generally administered orally and is often combined with other antibiotics to enhance its efficacy. However, it may cause side effects such as allergic reactions, skin rashes, and gastrointestinal disturbances in some individuals. Overall, disulfanilamide is a valuable and effective antibiotic for combating bacterial infections in clinical settings.

InChI:InChI=1/C12H13N3O4S2/c13-9-1-5-11(6-2-9)20(16,17)15-21(18,19)12-7-3-10(14)4-8-12/h1-8,15H,13-14H2

Upstream product

• 121-60-8 p-acetylaminobenzenesulfonyl chloride 
• 121-61-9 p-acetylaminobenzenesulfonamide 
• 103-84-4 Acetanilid 
• 63-74-1 sulfanilamide 

Relevant articles and documents

Effects of medium and substituents on dissociation of 4,4′-disubstituted bis(benzenesulfon)imides

Ten 4,4′-disubstituted bis(arenesulfon)imides of the general formula XC6H4SO2NHSO2C6H 4X have been synthesized and their structures confirmed by their 1H NMR spectra. Elemental analyses are presented for the compounds not yet described. The dissociation constants of these model substances have been measured potentiometrically in pyridine, dimethylformamide, methanol, ethanol, propylene carbonate, acetone, acetonitrile, 1,2-dichloroethane and tetramethylene sulfone. The pKHA values obtained have been correlated with three sets of the Hammett substituent constants and the results have been used to discuss the solvent and substituent effects on the dissociation of the compounds studied. Sulfonimides with electron-acceptor substituents behave as rather strong acids in some solvents (pyridine, dimethylformamide, methanol and ethanol), whereas normal substituent dependences are found in other solvents. The experimental data have also been interpreted with the help of the statistical methods based on latent variables. From the calculations it follows that only the first principal component, which correlates well with the substituent constant sets adopted, is statistically significant in describing the substituent effect on the acid-base process studied.