640282-47-9Relevant academic research and scientific papers
Efficient synthesis of 2-mono and 2,3-disubstituted indoles via palladium-catalyzed oxidation of aminoalcohols
Aoyagi, Yutaka,Shishikura, Masahiro,Mizusaki, Toshihiko,Komine, Takashi,Yoshinaga, Tokuji,Inaba, Haruko,Ohta, Akihiro,Takeya, Koichi
, p. 1055 - 1059 (2008/12/20)
Efficient synthesis of 2-mono- and 2,3-disubstituted indoles has been accomplished via palladium-catalyzed oxidation of aminoalcohols.
Heterocyclic ions from N-oxides of N-(4-nitrobenzylidene)-2-cyclopropylaniline and N-(4-nitrobenzylidene)-2-cyclopropylmethylaniline: Formation, isomerization, and conversions
Trofimova,Fedotov,Gazzaeva,Mochalov,Shabarov,Zefirov
, p. 205 - 212 (2007/10/03)
The N-oxide of N-(4-nitrobenzylidene)-2-cyclopropylaniline is converted by the action of strong acids into the corresponding 2,1-benzoxazinium derivative. Under identical conditions the N-oxide of N-(4-nitrobenzylidene)-2-cyclopropylmethylaniline forms the corresponding 2,1-benzoxazinium and 2,1-benzoxazepinium salts in a ratio of 1: 2. The 2,1-benzoxazepinium ions are thermodynamically less stable and are isomerized with time into 2,1-benzoxazinium ions. Treatment of 2,1-benzoxazinium salts with hydrobromic acid solution and subsequent neutralization leads to o-(2-hydroxyalkyl)anilines and p-nitrobenzaldehyde. The effect of the nature of the ortho substituent on the direction of the conversions of the corresponding arylcyclopropanes is discussed.
