640296-99-7Relevant articles and documents
Stereospecific Rearrangements during the Synthesis of Pyrrolidines and Related Heterocycles from Cyclizations of Amino Alcohols with Vinyl Sulfones
Back, Thomas G.,Parvez, Masood,Zhai, Huimin
, p. 9389 - 9393 (2003)
Conjugate additions of amino alcohols derived from α-amino acids to vinyl sulfones, followed by N-benzylation, chlorination, and intramolecular alkylation, provide a convenient route to substituted pyrrolidines. The process is accompanied by the stereospe