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5-Chlorobenzoxazol-2-yl-hydrazine is a chemical compound characterized by its molecular formula C7H6ClN3O. It is a hydrazine derivative featuring a benzoxazol ring with a chlorine substituent, which endows it with unique reactivity as a nucleophile. 5-CHLOROBENZOXAZOL-2-YL-HYDRAZINE is recognized as a potential intermediate in the synthesis of pharmaceuticals and agrochemicals, and its potential biological activities have garnered interest in both medicinal and agricultural research fields.

64037-22-5

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64037-22-5 Usage

Uses

Used in Pharmaceutical Industry:
5-Chlorobenzoxazol-2-yl-hydrazine is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its reactivity and structural features make it a valuable component in the development of new drugs, potentially contributing to the creation of novel therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 5-chlorobenzoxazol-2-yl-hydrazine serves as a precursor in the production of agrochemicals. Its involvement in the synthesis of compounds with pesticidal or herbicidal properties underscores its utility in developing effective solutions for crop protection and management.
Used in Organic Synthesis:
5-Chlorobenzoxazol-2-yl-hydrazine is utilized as a nucleophilic agent in organic synthesis. Its ability to participate in various chemical reactions allows for the creation of a wide range of organic compounds, expanding the scope of chemical research and development.
Used in Medicinal Research:
5-CHLOROBENZOXAZOL-2-YL-HYDRAZINE is employed in medicinal research for exploring its potential biological activities. Given its unique structure, 5-chlorobenzoxazol-2-yl-hydrazine may exhibit properties that could be harnessed for therapeutic purposes, making it a subject of interest for scientists investigating new treatments and pharmaceutical agents.
Used in Agricultural Research:
In agricultural research, 5-chlorobenzoxazol-2-yl-hydrazine is studied for its possible applications in enhancing crop yields and managing pests. Its potential to be incorporated into agrochemicals that promote plant health and protect against diseases positions it as a valuable asset in the agricultural sciences.

Check Digit Verification of cas no

The CAS Registry Mumber 64037-22-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,3 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 64037-22:
(7*6)+(6*4)+(5*0)+(4*3)+(3*7)+(2*2)+(1*2)=105
105 % 10 = 5
So 64037-22-5 is a valid CAS Registry Number.
InChI:InChI=1/C7H6ClN3O/c8-4-1-2-6-5(3-4)10-7(11-9)12-6/h1-3H,9H2,(H,10,11)

64037-22-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name (5-chloro-1,3-benzoxazol-2-yl)hydrazine

1.2 Other means of identification

Product number -
Other names BENZOXAZOLE,5-CHLORO-2-HYDRAZINO

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:64037-22-5 SDS

64037-22-5Downstream Products

64037-22-5Relevant academic research and scientific papers

Studies on novel rearangement of benzoxazolethiol

Swelam, Samira Abou-Srie,Abu-Bakr, Sherifa Mostafa

, p. 115 - 122 (2008/09/20)

A new chemoselective approach to synthesize a series of benzoimidazole 2a-c, 3, 4a, b and benzoxazol-2-thiol derivatives 5a-c, 6, 7a,b. Benzoxazol-2-thiol derivatives under action of N-nucleophiles, by using this methodology, two series of heterocyclic systems were synthesized. 7-Chloro-2-methyl/or aryl-benzo-[4,5]imidazo[1,2,4] thiadiazole derivatives 8,9 and 10a-c were prepared via cyclocondensation and condensation elimination reaction.

N1-Hetaryl substituted pyridine- and pyrazinecarboxamidrazones with antimycobacterial activity.

Ranft,Lehwark-Yvetot,Schaper,Buege

, p. 169 - 172 (2007/10/03)

A series of amidrazones was prepared and characterized by 1H NMR and mass spectroscopy. The substances were tested against M. tuberculosis, M. avium, M. intracellulare, and M. lufu. Compounds 11-13 exhibit a satisfactory inhibition of mycobacteria.

3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives: Inhibitors of immune complex induced inflammation

Haviv,Ratajczyk,DeNet,Kerdesky,Walters,Schmidt,Holms,Young,Carter

, p. 1719 - 1728 (2007/10/02)

3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives were evaluated in the dermal and pleural reverse passive Arthus reactions in the rat. In the pleural test these compounds were effective in reducing exudate volume and accumulation of white blood cells. This pattern of activity was similar to that of hydrocortisone and different from that of indomethacin. The structural requirements for inhibiting the Arthus reactions were studied by systematic chemical modification of 1. These structure-activity relationship studies revealed that nitrogen 1' of the hydrazino group is essential for activity and must be electron rich, whereas chemical modifications of other sites of 1 had only a modest effect on activity.

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