64047-46-7 Usage
Uses
Used in Pharmaceutical Research and Drug Development:
4-ISOTHIOCYANATO-N-PYRIMIDIN-2-YLBENZENESULFONAMIDE is used as a reactive intermediate in the synthesis of various pharmaceutical compounds due to its unique structure and potential pharmacological properties. Its presence in drug development can lead to the creation of novel therapeutic agents with specific target interactions and improved efficacy.
Used in Organic Synthesis:
In the field of organic synthesis, 4-ISOTHIOCYANATO-N-PYRIMIDIN-2-YLBENZENESULFONAMIDE serves as a key building block for the assembly of complex organic molecules. Its isothiocyanate and benzene sulfonamide functionalities can be exploited in various synthetic strategies, enabling the formation of a wide range of chemical products.
Used in Material Science:
4-ISOTHIOCYANATO-N-PYRIMIDIN-2-YLBENZENESULFONAMIDE is utilized in material science for the development of new materials with specific properties. Its incorporation into polymers, coatings, or other materials can lead to enhanced performance characteristics, such as improved stability, reactivity, or biological activity, depending on the application.
Check Digit Verification of cas no
The CAS Registry Mumber 64047-46-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,0,4 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 64047-46:
(7*6)+(6*4)+(5*0)+(4*4)+(3*7)+(2*4)+(1*6)=117
117 % 10 = 7
So 64047-46-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H8N4O2S2/c16-19(17,15-11-12-6-1-7-13-11)10-4-2-9(3-5-10)14-8-18/h1-7H,(H,12,13,15)
64047-46-7Relevant academic research and scientific papers
Synthesis, characterization and in vitro antimicrobial activity of novel 2-thioxo-4-thiazolidinones and 4,4′-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfones
El-Gaby, Mohamed S.A.,El-Hag Ali, Gameel A.M.,El-Maghraby, Ahmed A.,Abd El-Rahman, Mohamed T.,Helal, Mohamed H.M.
scheme or table, p. 4148 - 4152 (2009/12/06)
2-Thioxo-4-thiazolidinones (3a,b) were achieved by cyclocondensation of isothiocyanatosulfonamides (1a,b) with sulfanylacetic acid at reflux temperature in dioxane in the presence of triethylamine. Compound (3a) was exploited to synthesize the versatile hitherto unknown 2-thioxo-4-thiazolidinones (5-10) via its reaction with some electrophiles. Cyclization of 4,4′-diisothiocyanate diphenylsulfone (11) with sulfanylacetic acid furnished 4,4′-bis(2-thioxo-4-thiazolidinone-3-yl)diphenylsulfone (12) which on treatment with excess 4-methoxybenzaldehyde in refluxing dioxane in the presence of piperidine yielded the bisbenzylidene derivative (13). The novel synthesized compounds were characterized by IR, 1H NMR and mass spectral studies. All the synthesized compounds were screened in vitro for their antibacterial and antifungal activities.
