64064-19-3

Basic information

• Product Name: 8-chloro-2-ethyl-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]pyrrolo[1,2-a][1,4]diazepine
• CAS NO: 64064-19-3
• Molecular Weight: 352.839
• Mol File: 64064-19-3.mol

Chemical Properties

• CAS DataBase Reference: 8-chloro-2-ethyl-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]pyrrolo[1,2-a][1,4]diazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-chloro-2-ethyl-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]pyrrolo[1,2-a][1,4]diazepine(64064-19-3)
• EPA Substance Registry System: 8-chloro-2-ethyl-6-(2-fluoro-phenyl)-1-methyl-4H-benzo[f]pyrrolo[1,2-a][1,4]diazepine(64064-19-3)

Safety Data

• Hazardous Substances Data: 64064-19-3(Hazardous Substances Data)

Relevant articles and documents

Benzodiazepine derivatives and pharmaceutical compositions containing said derivatives

Novel 4H-pyrrolo[1,2-a][1,4]benzodiazepine derivatives of the formula STR1 wherein at least one of R1, R2 and R3 represent lower alkyl and the remainder hydrogen, R4 represents hydrogen or lower alkyl, ring A optionally contains at least one substituent selected from halogen, nitro and trifluoromethyl, and ring B optionally contains at least one substituent selected from halogen, nitro, trifluoromethyl, lower alkyl and lower alkoxy; and novel intermediates thereof expressed by the formula STR2 wherein Z represents protected amino. Compounds of formula (I) are prepared by subjecting compounds of formula (II) to protective group-elimination and cyclization. The compounds of formula (I) and acid addition salts thereof have useful anti-anxietic, sedative, anti-convulsant, muscle relaxant and hypnotic, and their toxicity is low.