64064-71-7

Basic information

• Product Name: 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE
• Synonyms: 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE;IMidazo[1,2-a]pyridine, 6-broMo-3-nitro-
• CAS NO: 64064-71-7
• Molecular Formula: C₇H₄BrN₃O₂
• Molecular Weight: 242.03
• Product Categories: Halides;Fused Ring Systems
• Mol File: 64064-71-7.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 1.98±0.1 g/cm3(Predicted)
• Refractive Index: 1.757
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -0.28±0.50(Predicted)
• CAS DataBase Reference: 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE(64064-71-7)
• EPA Substance Registry System: 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE(64064-71-7)

Safety Data

• Hazardous Substances Data: 64064-71-7(Hazardous Substances Data)

Usage

General Description

6-Bromo-3-Nitroimidazo[1,2-a]pyridine is a chemical compound with the molecular formula C7H4BrN3O2. 6-BROMO-3-NITROIMIDAZO[1,2-A]PYRIDINE is a nitroimidazole derivative and is commonly used in organic synthesis and pharmaceutical research. It is a potent and selective inhibitor of cyclin-dependent kinase (CDK) 2 and 5, making it a potential candidate for anti-cancer and neurodegenerative disease treatments. Additionally, it has been studied for its activity as an antimicrobial agent, particularly against parasitic infections. Its unique structure and biological activity make 6-Bromo-3-Nitroimidazo[1,2-a]pyridine an important compound in the development of new drugs and therapeutic treatments.

InChI:InChI=1/C7H4BrN3O2/c8-5-1-2-6-9-3-7(11(12)13)10(6)4-5/h1-4H

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 6188-23-4 6-bromoimidazo[1,2-a]pyridine 

Downstream Products

• 64064-73-9 3-amino-6-phenylthioimidazo [1,2-a] pyridine 
• 64064-74-0 (6-phenylsulfanyl-imidazo[1,2-a]pyridin-1-yl)-carbamic acid methyl ester 
• 64064-72-8 3-nitro-6-phenylsulfanyl-imidazo[1,2-a]pyridine 

Relevant articles and documents

SUBSTITUTED IMIDAZOPYRIDINES, THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS

This application relates to substituted imidazopyridines, compositions comprising them and their uses in the treatment of diseases and conditions in which inhibition of a bromodomain is indicated. For example, the application relates to substituted imidaz

Substituted imidazo [1,2-a] pyridines

Certain novel substituted imidazo [1,2-a] pyridines with a substituted amino group at the 2- or 3-position are active anthelmintic agents. The novel compounds are prepared from the appropriate substituted 2-aminopyridine precursor. Compositions which utilize said novel imidazo [1,2-a] pyridines as the active ingredient thereof for the treatment of helminthiasis are also disclosed.

Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group

Certain novel substituted imidazo [1,2-a] pyridines with a substituted amino group at the 2- or 3- position and a heterocyclic moiety on the pyrido portion of the molecule are active anthelmintic agents. The heterocyclic moiety is connected to the imidazo [1,2-a] pyridine molecule through an oxygen, sulfur, sulfinyl or sulfone. The novel compounds are prepared from the appropriately substituted 2-amino pyridine precursor. Compositions which utilize said novel imidazo [1,2-a] pyridines as the active ingredient thereof for the treatment of helminthiasis are also disclosed.