640721-07-9

Upstream product

• 640721-02-4 6-bromo-4-hydroxymethyl-7-(methoxymethoxy)-2H-chromen-2-one 
• 4326-36-7 (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester 
• 640721-03-5 [[6-bromo-7-(methoxymethoxy)coumarin-4-yl]methoxy]carbonyl chloride 

Relevant academic research and scientific papers

Coumarin-4-ylmethoxycarbonyls as Phototriggers for Alcohols and Phenols

(Equation Presented) Caged compounds can be used to regulate the spatial and temporal dynamics of signaling molecules in live cells. Photochemical properties of coumarin-4-ylmethoxy carbonates (1a-d) are investigated to construct caged compounds of hydroxy-containing molecules. All the compounds possess desired properties as phototriggers for alcohols and phenols. The 6-bromo-7-hydroxycoumarin-4-ylmethoxycarbonyl (Bhcmoc) group has the highest photochemical efficiency and is applied to make caged compounds of 1,2-dioctanoylglycerol (diC8), Tyr-OMe, and adenosine.