640735-25-7 Usage
Uses
Used in Medicinal Chemistry:
1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-1-[tris(1-methylethyl)silyl]is used as a key intermediate in the synthesis of pharmaceutical compounds for drug development. Its unique structure and potential biological activity contribute to the discovery of new therapeutic agents.
Used in Biochemistry:
In biochemistry, 1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-1-[tris(1-methylethyl)silyl]serves as a valuable research tool for studying molecular interactions and mechanisms. Its potential biological activity allows scientists to explore its effects on biological systems and pathways.
Used in Organic Synthesis:
1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-1-[tris(1-methylethyl)silyl]is used as a protecting group in organic synthesis to shield functional groups during chemical reactions. This ensures the selective modification of specific sites on a molecule, facilitating the synthesis of complex organic compounds.
Used in Drug Development:
In the pharmaceutical industry, 1H-Pyrrolo[2,3-b]pyridine, 4-fluoro-1-[tris(1-methylethyl)silyl]is utilized in the development of new drugs. Its unique structure and potential pharmacological properties make it a valuable asset in the search for novel therapeutic agents to treat various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 640735-25-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,4,0,7,3 and 5 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 640735-25:
(8*6)+(7*4)+(6*0)+(5*7)+(4*3)+(3*5)+(2*2)+(1*5)=147
147 % 10 = 7
So 640735-25-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H25FN2Si/c1-11(2)20(12(3)4,13(5)6)19-10-8-14-15(17)7-9-18-16(14)19/h7-13H,1-6H3
640735-25-7Relevant academic research and scientific papers
KINASE ANTAGONISTS AND METHODS FOR MAKING AND USING THEM
-
Page/Page column 102-103, (2020/02/19)
Disclosed herein are small molecule compounds that are SGK1 antagonists, formulations and pharmaceutical compositions comprising the compounds, and methods of making and using them, for treating, ameliorating, preventing, reversing or slowing the progression of: a cancer, a tumor, a metastasis or a dysplastic or a dysfunctional cell condition responsive to inhibition of a kinase enzyme of the AGC group of kinases including SGK1, by administration of an AGC kinase inhibitor or antagonist.
Synthesis of 4-(cyclic dialkylamino)-7-azaindoles by microwave heating of 4-halo-7-azaindoles and cyclic secondary amines
Caldwell, John J.,Cheung, Kwai-Ming,Collins, Ian
, p. 1527 - 1529 (2008/02/02)
Nucleophilic aromatic substitution of 4-chloro- and 4-fluoro-7-azaindoles with cyclic secondary amines under microwave heating gave a straightforward and rapid synthesis of 4-(cyclic dialkylamino)-7-azaindoles. 4-Fluoro-7-azaindoles showed a greater reactivity towards SNAr reactions under these conditions than 4-chloro-7-azaindole.
