64080-67-7

Basic information

• Product Name: 2,5-Cyclohexadiene-1,4-dione, 2,5-dichloro-3-methyl-6-[3-(phenylmethoxy)-1-propynyl]-
• CAS NO: 64080-67-7
• Molecular Formula: C17H12Cl2O3
• Molecular Weight: 335.186
• Mol File: 64080-67-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,5-Cyclohexadiene-1,4-dione, 2,5-dichloro-3-methyl-6-[3-(phenylmethoxy)-1-propynyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Cyclohexadiene-1,4-dione, 2,5-dichloro-3-methyl-6-[3-(phenylmethoxy)-1-propynyl]-(64080-67-7)
• EPA Substance Registry System: 2,5-Cyclohexadiene-1,4-dione, 2,5-dichloro-3-methyl-6-[3-(phenylmethoxy)-1-propynyl]-(64080-67-7)

Safety Data

• Hazardous Substances Data: 64080-67-7(Hazardous Substances Data)

Upstream product

• 7210-71-1 2,5-dichloro-3,6-dimethoxy-1,4-benzoquinone 
• 917-54-4 methyllithium 
• 64080-63-3 C₁₀H₉LiO 
• 4039-82-1 Benzyl propargyl ether 

Relevant articles and documents

Synthesis of Substituted Quinones. 2,5-Disubstituted 1,4-Benzoquinones

Synthetic methodology is presented which allows the facile synthesis of 2,5-disubstituted 1,4-benzoquinones.This involves the initial 1,2-addition of an alkynyllithium reagent to one of the carbonyl groups of 2,5-diethoxy- or 2,5-dichloro-3,6-dimethoxy-1,4-benzoquinone.This is followed by an analogous addition of an alkyl-, aryl-, or alkynyllithium to the remaining carbonyl to give a cyclohexa-2,5-diene-1,4-diol derivative.Acid hydrolysis of these adducts results in the 2,5-dialkylated 1,4-benzoquinones.This methodology was employed to prepare 7-chloro-6-methyl-1,2,5,8-tetrahydro-3H-pyrroloindole-5,8-dione (14), a compound having the basic ring systeme of the mitomycin antineoplastic antibiotics.