64097-94-5

Basic information

• Product Name: Quinoline, 2-(4-methyl-1-piperazinyl)-4-phenyl-
• CAS NO: 64097-94-5
• Molecular Formula: C20H21N3
• Molecular Weight: 303.407
• Mol File: 64097-94-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Quinoline, 2-(4-methyl-1-piperazinyl)-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline, 2-(4-methyl-1-piperazinyl)-4-phenyl-(64097-94-5)
• EPA Substance Registry System: Quinoline, 2-(4-methyl-1-piperazinyl)-4-phenyl-(64097-94-5)

Safety Data

• Hazardous Substances Data: 64097-94-5(Hazardous Substances Data)

Upstream product

• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 5855-57-2 4-phenyl-2-quinolinone 
• 85-99-4 2-acetamidobenzophenone 
• 521270-76-8 (2-isocyanophenyl)(phenyl)methanone 
• 54567-10-1 N-(2-benzoylphenyl)-formamide 
• 109-01-3 1-methyl-piperazine 
• 521270-79-1 1-isocyano-2-(2-methoxy-1-phenylethenyl)benzene 
• 5855-56-1 2-chloro-4-phenylquinoline 

Relevant articles and documents

A convenient synthesis of quinolines by reactions of o-isocyano-β- methoxystyrenes with nucleophiles

2,4-Disubstituted quinolines have been synthesized by reactions of o-isocyano-β-methoxystyrenes, which can be easily prepared from commercially available o-aminophenyl ketones in three steps, with alkyl(or aryl)lithiums in generally good yields. Subsequently, o-isocyano-β- methoxystyrenes have also proved to react efficiently with lithium dialkylamides to afford the corresponding 4-substituted N,N-dialkylquinolin-2-amines in satisfactory yields. Graphical Abstract.