6412-89-1

Basic information

• Product Name: 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE
• Synonyms: 4-(3,4-METHYLENEDIOXYBENZYLIDENE)-2-PHENYL-5-OXAZOLONE;4-(3,4-METHYLENEDIOXYBENZAL)-2-PHENYL-5-OXAZOLONE;4-(1,3-BENZODIOXOL-5-YLMETHYLENE)-2-PHENYL-5(4H)-OXAZOLONE;2-Phenyl-4-(1,3-benzodioxol-5-ylmethylene)oxazol-5(4H)-one;2-Phenyl-4-(1,3-benzodioxole-5-ylmethylene)-2-oxazoline-5-one;2-Phenyl-4-(3,4-methylenebisoxybenzylidene)oxazol-5(4H)-one;TIMTEC-BB SBB008069;PIPERONAL AZLACTONE
• CAS NO: 6412-89-1
• Molecular Formula: C₁₇H₁₁NO₄
• Molecular Weight: 293.27
• Mol File: 6412-89-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 443.7°C at 760 mmHg
• Flash Point: 205.1°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 4.56E-08mmHg at 25°C
• Refractive Index: 1.658
• CAS DataBase Reference: 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE(6412-89-1)
• EPA Substance Registry System: 2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE(6412-89-1)

Safety Data

• Hazardous Substances Data: 6412-89-1(Hazardous Substances Data)

Usage

General Description

2-PHENYL-4-PIPERONYLIDENE-2-OXAZOLIN-5-ONE, also known as PPO, is a chemical compound with the molecular formula C17H13NO3. It is a yellowish-brown solid with a melting point of 168-170°C. PPO is widely used as a photoinitiator in UV-curing applications, such as inks, coatings, and adhesives. It absorbs UV light and undergoes a photoreaction to produce free radicals, which initiate the polymerization process. PPO is also used as a crosslinking agent in the synthesis of polymers and as a pharmaceutical intermediate. However, it is important to handle PPO with caution, as it may cause skin and eye irritation and is harmful if ingested or inhaled.

InChI:InChI=1/C17H11NO4/c19-17-13(18-16(22-17)12-4-2-1-3-5-12)8-11-6-7-14-15(9-11)21-10-20-14/h1-9H,10H2/b13-8-

Upstream product

• 19747-01-4 3-benzo[1,3]dioxol-5-yl-2-benzoylamino-acryloyl azide 
• 1199-01-5 2-phenylazlactone 
• 120-57-0 piperonal 
• 495-69-2 Hippuric Acid 
• 108-24-7 acetic anhydride 
• 19746-92-0 4-benzo[1,3]dioxol-5-ylmethylene-6-phenyl-3,4-dihydro-[1,3,5]oxadiazin-2-one 
• 70984-52-0 3-benzo[1,3]dioxol-5-yl-2-benzoylamino-acrylic acid 
• 532-94-5 sodium hippurate 

Downstream Products

• 109255-64-3 3-benzo[1,3]dioxol-5-yl-2-benzoylamino-acrylohydroxamic acid 
• 101883-61-8 4-(benzo[1,3]dioxol-5-yl-chloro-methylene)-2-phenyl-4H-oxazol-5-one 
• 101883-55-0 4-(benzo[1,3]dioxol-5-yl-bromo-methylene)-2-phenyl-4H-oxazol-5-one 
• 1273258-22-2 1,4:3,6-dianhydro-2,5-bis-[2-benzamido-(Z)-3,4-methylenedioxycinnamamido]-2,5-dideoxy-L-iditol 
• 1260526-22-4 C₃₀H₂₂N₂O₄ 
• 1260525-93-6 C₂₄H₁₈N₄O₄ 
• 433690-59-6 C₁₈H₁₆N₂O₄ 
• 75793-16-7 (4Z)-4-[(2H-1,3-benzodioxol-5-yl)methylidene]-2-phenyl-4,5-dihydro-1H-imidazol-5-one 
• 1361559-79-6 (1S,5R)-2-ethyl 1-methyl-1-benzamido-5-(benzo[d][1,3]dioxol-5-yl)cyclopent-2-ene-1,2-dicarboxylate 

Relevant articles and documents

A convenient synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones under solvent-assisted grinding

A facile and effective approach for the synthesis of 4-arylidene-2-phenyl-5(4H)-oxazolones has been developed. Under solvent-assisted grinding in the presence of 2,4,6-trichloro-1,3,5-triazine, catalytic triphenylphosphine, and sodium carbonate, dehydrati

Novel peptide mimetic inhibitors of hepatitis C serine protease derived from isomannide

Hepatitis C (HCV) infection is a cause of chronic liver disease such as cirrhosis, carcinoma, or liver failure, and the current therapy is effective in only 50% of patients. Serine proteases, which are present in HCV, are the most studied class of proteolytic enzymes, and are a primary target in the drug development field. In this paper, we describe the synthesis and biological studies of a novel class of peptide mimetic compounds as potential HCV serine protease inhibitors. Georg Thieme Verlag Stuttgart.

Three distinct reactions of 3,4-dihydroisoquinolines with azlactones: Novel synthesis of imidazoloisoquinolin-3-ones, benzo[a]quinolizin-4-ones, and benzo[d]azocin-4-ones

(Diagram presented) A facile and direct synthetic entry to tricyclic imidazoloisoquinolin-3-ones and benzo[a]quinolizin-4-ones is reported based on the ring annulation of 1-unsubstituted and 1-substituted dihydroisoquinolines with azlactones under neutral