64152-92-7Relevant academic research and scientific papers
SYNTHESIS AND INVESTIGATION OF THE BIOLOGICAL ACTIVITY OF SHORTENED ANALOGUES OF LULIBERIN
Burov, S. V.,Nikolaev, S. V.,Korhkov, V. V.,Lupanova, G. E.,Makusheva, V. P.
, p. 496 - 499 (2007/10/02)
Five new luliberin analogues with shortened amino acid sequences have been synthesized.The different variants for obtaining the compounds under consideration are discussed.In an investigation of the biological activities of the analogues it was shown that
SYNTHESIS OF BIOLOGICALLY ACTIVE ANALOGS OF LULIBERIN WITH SHORTENED AMINO ACID SEQUENCES
Burov, S. V.,Nikolaev, S. V.,Smironova, M. P.,Lupanova, G. E.,Bobrov, Yu. F.,et al.
, p. 732 - 737 (2007/10/02)
Two new analogs of the releasing factor of the luteinizing hormone with shortened amino acid sequences have been synthesized by the methods of classical peptide chemistry.The influence of the preparations on the action of chorionic gonadotropin and on the
SYNTHESIS OF 3(NH2); Pro3; D-Ala6>- and 2(NO2); Pro3; D-Ala6>LULIBERINS
Burov, S. V.,Kaurov, O. A.,Martynov, V. F.,Smirnova, M. P.
, p. 518 - 524 (2007/10/02)
In order to study the influence of substituents of the aromatic ring of D-phenylalanine on the inhibiting capacity of luliberian analogs, we have synthesized two new analogs: 2; Pro3; D-Ala6>- and
Octapeptides and methods for their production
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, (2008/06/13)
New octapeptides having the formula Prot Grp-R-Trp-Ser-Tyr-R2 -Leu-Arg-Pro-R3 ; salts thereof; wherein R is Gln, Gln (bzl), His (bzl), Ser (bzl), Pro, Leu, Tyr (bzl), Ile, Cys (bzl) or Phe, R2 is D-Phe, D-Ala, D-Leu, D-Trp, D-Tyr, D-Tyr (Me), D-Ser, D-Met, D-Arg, D-Val, D-His, D-Gln, D-Phs, D-Thr, D-Pro, D-Me5 Phe or D-Asn and R3 is NH2, NH(lower alkyl), N-(lower alkyl)2, NH-benzyl, NHCH2 CH2 N-(lower alkyl)2 or NH-CH2 CH2 SO2 NH-benzyl; methods for their production; certain peptide intermediates and their salts used in the production thereof; and the use of said octapeptides as luteinizing hormone releasing factor antagonists.
