64157-87-5 Usage
Uses
Used in Oncology:
[4-(3-[(2-chloroethyl)sulfanyl]propanoylamino)phenyl]phosphonic acid is used as an alkylating agent for the treatment of various forms of cancer. It is particularly effective in treating testicular cancer and some types of soft tissue sarcomas. As a prodrug, it is converted into its active form in the body, where it disrupts DNA replication and induces cell death, exerting its cytotoxic effects on cancer cells.
Check Digit Verification of cas no
The CAS Registry Mumber 64157-87-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,4,1,5 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 64157-87:
(7*6)+(6*4)+(5*1)+(4*5)+(3*7)+(2*8)+(1*7)=135
135 % 10 = 5
So 64157-87-5 is a valid CAS Registry Number.
64157-87-5Relevant academic research and scientific papers
Chemoimmunotherapy of cancer
Soloway,Wright,Subramanyam,Gozzo
, p. 1357 - 1362 (2007/10/05)
The preparation of a series of water-soluble mustard haptens for chemoimmunotherapy of cancer is described. Preliminary screening data are given, indicating some activity against P388 lymphocytkc leukemia for those compounds containing the most potent immunogenic functional groups.
