6416-55-3

Usage

InChI:InChI=1/C22H18ClF3N2O3S/c1-15-7-10-18(11-8-15)32(30,31)28(17-5-3-2-4-6-17)14-21(29)27-16-9-12-20(23)19(13-16)22(24,25)26/h2-13H,14H2,1H3,(H,27,29)

Upstream product

• 20990-82-3 1-bromo-4-hydroxy-2-methyl-anthraquinone 
• 109059-72-5 1,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2,3-dicarboxylic acid-anhydride 
• 860561-79-1 2'-chloro-5'-methoxy-2,4'-carbonyl-di-benzoic acid 
• 5470-98-4 1,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2,3-dicarbonitrile 
• 392248-86-1 1,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2,3-dicarboxylic acid 
• 20990-83-4 1,4-Diacetoxy-2-methyl-9,10-anthrachinon 
• 108-24-7 acetic anhydride 
• 154658-41-0 9,10-Dihydro-1,4-dimethoxy-9,10-dioxoanthracene-2-carboxylic acid 
• 7664-93-9 sulfuric acid 
• 860730-16-1 1,4-dihydroxy-9,10-dioxo-9,10-dihydro-anthracene-2-carboxylic acid amide 
• 13460-50-9 metaboric acid 
• 59359-67-0 3-methyl-1-hydroxy-4-chloroanthraquinone 
• 81-64-1 1,4-dihydroxy-9,10-anthracenedione 
• 25060-18-8 2,3-dimethyl quinizarine 

Downstream Products

• 1709-63-3 anthracene-1,4,9,10-tetraone 
• 476-41-5 pseudopurpurin 

Relevant academic research and scientific papers

Pharmaceutical compounds

Pharmaceutical compounds of the formula STR1 in which R1 and R2 are each hydrogen, hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl-C1-4 alkoxy; R3 is tetrazolyl, or and R4 and R5 are each hydrogen, hydroxy, acyloxy, nitro, C1-4 alkyl, C1-4 alkoxy, halo, optionally substituted phenyl, --SO3 H or --NR'R" where R' and R" are each hydrogen or C1-4 alkyl; provided that when R3 is --CR'R".CHR'"CO2 H or tetrazolyl, R1 and R2 are each hydroxyl, halo, C1-4 alkyl, C1-4 alkoxy, acyloxy, --O-glucoside, optionally substituted phenyl or optionally substituted phenyl C1-4 alkoxy; and or a pharmaceutically acceptable salt or ester thereof.

A VERSATILE SYNTHESIS OF HYDROXY-9,10-ANTHRAQUINONE-2-CARBOXYLIC ACIDS

Islandicin, a mould metabolite, can be synthesised in a few, robust, high yielding steps.This procedure can be further elaborated to give a variety of hydroxy-9,10-anthraquinone-2-carboxylic acids.