641609-29-2Relevant academic research and scientific papers
Kinetic resolution and parallel kinetic resolution of methyl (±)-5-alkyl-cyclopentene-l-carboxylates for the asymmetric synthesis of 5-alkyl-cispentacin derivatives
Davies, Stephen G.,Garner, A. Christopher,Long, Marcus J. C.,Morrison, Rachel M.,Roberts, Paul M.,Savory, Edward D.,Smith, Andrew D.,Sweet, Miles J.,Withey, Jonathan M.
, p. 2762 - 2775 (2007/10/03)
Conjugate addition of lithium dibenzylamide to methyl 5-isopropyl, 5-phenyl- and 5-tert-butyl-cyclopentene-1-carboxylates occurs with high levels of substrate control (>88% de), with preferential addition to the face of the cyclic α,β-unsaturated acceptor
Preparation of methyl (1R,2S,5S)- and (1S,2R,5R)-2-amino-5-terf-butyl- cyclopentane-1-carboxylates by parallel kinetic resolution of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate
Davies, Stephen G.,Diez, David,El Hammouni, Mohamed M.,Garner, A. Christopher,Garrido, Narciso M.,Long, Marcus J. C.,Morrison, Rachel M.,Smith, Andrew D.,Sweet, Miles J.,Withey, Jonathan M.
, p. 2410 - 2411 (2007/10/03)
Comparison of the kinetic and parallel kinetic resolutions of methyl (RS)-5-tert-butyl-cyclopentene-1-carboxylate allows for the efficient synthesis of both (1R,2S,5S)- and (1S,2R,5R)-enantiomers of methyl 2-amino-5-tert-butyl- cyclopentane-1-carboxylate.
