641612-68-2

Upstream product

• 641612-67-1 1-(2-Fluoro-4-iodophenyl)-3-hydroxy-piperidin-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 641612-69-3 1-[3-fluoro-4-(3-hydroxy-2-oxopiperidin-1-yl)phenyl]piperidin-2-one 

Relevant academic research and scientific papers

Sulfonylaminovalerolactams and derivatives thereof as factor Xa inhibitors

The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.