641613-75-4

Upstream product

• 641613-72-1 Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester 
• 641613-71-0 (E)-(4R,5R)-7-(tert-Butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enoic acid ethyl ester 
• 641613-70-9 (2R,3R)-5-(tert-Butyl-dimethyl-silanyloxy)-2,3-bis-(4-methoxy-benzyloxy)-pentan-1-ol 
• 641613-77-6 Acetic acid (E)-(4R,5R)-7-hydroxy-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester 
• 641613-73-2 Acetic acid (E)-(4R,5R)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-7-oxo-hept-2-enyl ester 

Downstream Products

• 797035-82-6 4-[6-(4-{2-[6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-(4-methoxy-benzyloxy)-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazol-2-ylmethyl)-4,6-dimethoxy-tetrahydro-pyran-2-yl]-2-methyl-4-triisopropylsilanyloxy-but-2-enal 
• 797035-81-5 4-[6-(4-{2-[6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-4-(4-methoxy-benzyloxy)-3,5-dimethyl-tetrahydro-pyran-2-yl]-propenyl}-oxazol-2-ylmethyl)-4,6-dimethoxy-tetrahydro-pyran-2-yl]-2-methyl-4-triisopropylsilanyloxy-but-2-en-1-ol 
• 797035-80-4 C₆₆H₁₀₃NO₁₀Si₃ 
• 797035-67-7 C₆₇H₉₈BrNO₁₀Si₂ 
• 797035-70-2 (E)-(3R,5R,6R)-9-Hydroxy-3-methoxy-5,6-bis-(4-methoxy-benzyloxy)-8-methyl-non-7-enoic acid ethyl ester 

Relevant academic research and scientific papers

Total synthesis of phorboxazole B

An efficient and highly convergent total synthesis of the potent antitumor agent phorboxazole B has been achieved. The synthetic strategy of this synthesis features: 1) a highly efficient substrate-controlled hydrogenation to construct the functionalized

Studies on the synthesis of phorboxazole B: Stereoselective synthesis of the C28-C46 segment

A stereoselective synthesis of C28-C46 segment of phorboxazole B is described. Key features of the synthetic route involved the use of 1,3-asymmetric induction of Mukaiyama aldol reaction to construct the stereogenic center at C35, and the employment of m