64179-17-5

Usage

Uses

Used in Organic Synthesis:
2-Iodomethyl-1,4-Dioxane is used as a reagent in organic synthesis for the preparation of pharmaceuticals and agrochemicals. Its unique chemical properties make it a valuable component in the creation of various organic compounds.
Used in Chemical Manufacturing:
2-IODOMETHYL-1,4-DIOXANE also serves as an intermediate in the manufacturing of other chemicals, contributing to the production of a wide range of chemical products.
Used in Industrial Processes:
Furthermore, 2-Iodomethyl-1,4-Dioxane is utilized as a solvent in certain industrial processes, where its solvent properties are harnessed to facilitate specific reactions or processes.
It is crucial to handle 2-Iodomethyl-1,4-Dioxane with care due to its classification as an irritant. It may pose risks if ingested, inhaled, or comes into contact with the skin, and it may have environmental and health hazards if not managed and disposed of properly.

InChI:InChI=1/C5H9IO2/c6-3-5-4-7-1-2-8-5/h5H,1-4H2

Upstream product

• 111-45-5 ethylene glycol monoallyl ether 
• 74-88-4 methyl iodide 

Downstream Products

• 329217-47-2 2-piperazinylmethyl-1,4-dioxane 
• 68391-40-2 acetoxymethyl-[1,4]dioxane 
• 1112169-37-5 rac-6-(2-((1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-N-(4-fluoro-3-methoxybenzyl)-2-methyl-pyrimidine-4-carboxamide 
• 1112169-35-3 rac-6-(2-((1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-N-(3-methoxybenzyl)-2-methyl-pyrimidine-4-carboxamide 
• 329217-45-0 1-phenylmethyl-4(dioxan-2-ylmethyl)piperazine 

Relevant academic research and scientific papers

6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS

The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.

NOVEL INDOLE DERIVATIVES AND THEIR USE IN NEURODEGENERATIVE DISEASES

The present invention relates to indole compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders.

Benzimidazole compound

An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.

Halocyclization of Unsaturated Alcohols and Carboxylic Acids Using Bis(sym-collidine)iodine(I) Perchlorate

Reaction of I(collidine)2(1+) ClO4(1-) with unsaturated alcohols and carboxylic acids in dichloromethane at ambient temperature has afforded three- to seven-membered-ring iodoethers and four- to seven-membered-ring iodolactones, respectively, in moderate