64180-07-0

Basic information

• Product Name: 5-Amino-1-methylindoline 97%
• Synonyms: 5-Amino-1-methylindoline 97%;1-METHYL-5-INDOLINAMINE;5-Amino-1-methylindoline;5-Amino-1-methyl-2,3-dihydro-1H-indole;5-Amino-2,3-dihydro-1-methyl-1H-indole, 2,3-Dihydro-1-methyl-1H-indol-5-amine;1-Methyl-2,3-dihydro-1H-indol-5-ylamine
• CAS NO: 64180-07-0
• Molecular Formula: C9H12N2
• Molecular Weight: 148.21
• Mol File: 64180-07-0.mol

Chemical Properties

• Melting Point: 37.5-38.5°C
• Boiling Point: 331.95°C at 760 mmHg
• Flash Point: 129.242°C
• Appearance: /
• Density: 1.124g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.62
• PKA: 7.76±0.20(Predicted)
• CAS DataBase Reference: 5-Amino-1-methylindoline 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-1-methylindoline 97%(64180-07-0)
• EPA Substance Registry System: 5-Amino-1-methylindoline 97%(64180-07-0)

Safety Data

• Hazardous Substances Data: 64180-07-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Amino-1-methylindoline 97% is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs with specific therapeutic properties.
Used in Dye and Pigment Production:
In the dye and pigment industry, 5-Amino-1-methylindoline 97% is utilized as a building block for creating a variety of dyes and pigments, enhancing their color characteristics and performance in different applications.
Used in Fine Chemicals Synthesis:
5-Amino-1-methylindoline 97% is employed as a crucial component in the synthesis of fine chemicals, where its unique properties are leveraged to produce specialty chemicals for specific applications.
Used in Research and Development:
With its high purity, 5-Amino-1-methylindoline 97% is an essential ingredient in research and development processes, ensuring consistent and reliable performance in experiments and the creation of new chemical entities.
Used in Manufacturing Processes:
In manufacturing, 5-Amino-1-methylindoline 97% is incorporated into the production of a wide range of essential products, contributing to the chemical industry's ability to meet diverse market demands.

InChI:InChI=1/C9H12N2/c1-11-5-4-7-6-8(10)2-3-9(7)11/h2-3,6H,4-5,10H2,1H3

Upstream product

• 106883-07-2 4-(1-methyl-indolin-5-ylazo)-benzenesulfonic acid 
• 824-21-5 N-methylindoline 
• 18711-25-6 1-Methyl-5-nitroindoline 
• 32692-19-6 5-nitro-2,3-dihydro-1H-indole 

Downstream Products

• 10075-52-2 5-bromo-1-methyl-H-indole 
• 102308-97-4 1-methyl-1H-indol-5-amine 
• 412966-69-9 N-(1-methyl-indol-5-yl)-benzamide 

Relevant articles and documents

IMIDAZOPYRIDINES AS A NOVEL SCAFFOLD FOR MULTI-TARGETED KINASE INHIBITION

Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed. Formula (I).

ANTIFUNGAL AGENTS

Compounds of formula (I), and pharmaceutically acceptable salts thereof, may be used in therapy, for example as antifungal agents: (I) wherein: Rl, R2, R3, R4, R5, R6, R7, X and X1 are as defined herein. Certain compounds of formula (I) are also provided. Compounds of formula (T), and agriculturally acceptable salts thereof, may also be used as agricultural fungicides.

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The invention concerns quinazoline derivatives of Formula (I) or a pharmaceutically-acceptable salt, solvate or pro-drug thereof, wherein each of p, R1, q, R2, R3, R4, R5, Ring A, X1, R6, r and R7 has any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders or in the treatment of disease states associated with angiogenesis and/or vascular permeability.

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