64191-13-5

Usage

Uses

Used in Pharmaceutical Industry:
(1S,2S)-(-)-2-Amino-1-cyclopentanecarboxylic acid is utilized as a key building block for the synthesis of various pharmaceutical compounds. Its unique structure and properties make it an essential component in the development of new drugs, contributing to the advancement of medicinal treatments.
Used in Medicinal Chemistry and Drug Design:
In the realm of medicinal chemistry, (1S,2S)-(-)-2-Amino-1-cyclopentanecarboxylic acid is employed as a crucial element in the design and development of novel therapeutic agents. Its distinctive cyclopentane ring structure offers a versatile platform for the creation of innovative drugs with potential applications in various medical fields.
Used in Biochemistry:
(1S,2S)-(-)-2-Amino-1-cyclopentanecarboxylic acid also finds application in the field of biochemistry, where it aids in the study of complex biological processes. Its presence in biochemical research facilitates a deeper understanding of the mechanisms and interactions within living organisms.
Used as a Research Reagent in Chemical and Biological Laboratories:
In both chemical and biological research settings, (1S,2S)-(-)-2-Amino-1-cyclopentanecarboxylic acid serves as a valuable reagent. Its use in laboratory experiments supports the exploration of chemical reactions and biological phenomena, furthering scientific knowledge and discovery.

InChI:InChI=1/C6H11NO2/c7-5-3-1-2-4(5)6(8)9/h4-5H,1-3,7H2,(H,8,9)/t4-,5-/m0/s1

Upstream product

• 136237-71-3 (trans-(1S,2S)-2-aminocyclopentanecarbonyl)-(R)-(+)-α-methylbenzylamine 
• 188818-72-6 (+)-tert-butyl (1S,2S)-2-aminocyclopentane-1-carboxylate 
• 136237-70-2 -(R)-(+)-α-methylbenzylamine 
• 136315-71-4 (±)-trans-2-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid 
• 611-10-9 2-ethoxycarbonyl-1-cyclopentanone 
• 909786-18-1 (+)-tert-butyl (1S,2S)-2-(N-chloro-N-(mesitylmethyl)amino)cyclopentanecarboxylate 
• 909786-07-8 (+)-tert-butyl (1R,2S)-2-((mesitylmethyl)amino)cyclopentanecarboxylate 
• 909786-12-5 (+)-tert-butyl (1S,2S)-2-((mesitylmethyl)amino)cyclopentanecarboxylate 
• 359586-68-8 (1S,2S)-2-[(1'S)-phenylethyl]aminocyclopentanecarboxylic acid 
• 359586-66-6 ethyl (1S,2S)-2-[(1'S)-phenylethyl]aminocyclopentane-1-carboxylate 

Downstream Products

• 136315-66-7 N-(benzyloxycarbonyl)-β-benzyl-L-aspartyl-trans-(1S,2S)-2-aminocyclopentanecarboxylic acid methyl ester 
• 143679-80-5 (1S)-trans-2-<<(1,1-dimethylethoxy)carbonyl>amino>cyclopentanecarboxylic acid 

Relevant academic research and scientific papers

Chiral ligand-controlled asymmetric conjugate amination of enoates with lithium mesitylmethyl(trimethylsilyl)amide

Lithium mesitylmethyl(trimethylsilyl)amide behaved as a nice amination agent in a chiral ligand-controlled conjugate addition reaction of tert-butyl cinnamate to give the conjugate amination product with 99% ee in 90% yield. Other acyclic and cyclic enoat

Catalytic enantioselective desymmetrization of meso-N-acylaziridines with TMSCN

A catalytic enantioselective desymmetrization of meso-N-p-nitrobenzoylaziridines with TMSCN was developed using a chiral gadolinium catalyst generated from Gd(OiPr)3 and d-glucose-derived ligand 1. In this reaction, the addition of a

(S,S)-trans-cyclopentane-constrained peptide nucleic acids. A general backbone modification that improves binding affinity and sequence specificity

Replacing the ethylenediamine portion of aminoethylglycine peptide nucleic acids (aegPNAs) with one or more (S,S)-trans-cyclopentane diamine units significantly increases binding affinity and sequence specificity to complementary DNA, making these modifie

Probing a Molecular Model of Taste Utilizing Peptidomimetic Stereoisomers of 2-Aminocyclopentanecarboxylic Acid Methyl Ester

On the basis of the preferred conformations of L-aspartyl dipeptide derivatives containing α-amino acids at the second position and their retro-inverso analogues deduced by a combination of X-ray crystallography, 1H NMR spectroscopy, and molecular mechani