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CAS

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642-83-1

Aceglatone is a synthetic chemical compound that functions as an inhibitor of the angiotensin-converting enzyme (ACE), a key enzyme involved in the regulation of blood pressure and fluid balance within the body. Its ability to inhibit ACE can lead to a reduction in blood pressure and a decreased risk of cardiovascular diseases such as hypertension and heart failure. Additionally, Aceglatone possesses anti-inflammatory properties and can enhance endothelial function, making it a promising candidate for the treatment of conditions like diabetes and atherosclerosis. Currently, it is under investigation for its potential therapeutic applications in managing cardiovascular and inflammatory diseases.

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  • 642-83-1 Structure

  • Basic information

    1. Product Name: Aceglatone
    2. Synonyms: Aceglatone;(2-acetyloxy-3,7-dioxo-4,8-dioxabicyclo[3.3.0]oct-6-yl) acetate;2,5-Di-O-acetyl-D-glucaro-(1→4:6→3)-dilactone;2,5-di-O-Acetyl-D-glucosaccharo-(1→4:6→3)-dilactone;D-Glucaric acid, di-γ-lactone, 2,5-diacetate;Furo[3,2-b]furan, D-glucaric acid deriv.;Glucaric acid, 1,4:6,3-dilactone, diacetate (7CI);Glucaric acid, di-γ-lactone, diacetate, D- (8CI)
    3. CAS NO:642-83-1
    4. Molecular Formula: C10H10O8
    5. Molecular Weight: 258.18
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 642-83-1.mol

  • Chemical Properties

    1. Melting Point: 185-186° (Hirasaka)
    2. Boiling Point: 490°C at 760 mmHg
    3. Flash Point: 224°C
    4. Appearance: /
    5. Density: 1.49
    6. Vapor Pressure: 9.48E-10mmHg at 25°C
    7. Refractive Index: 1.511
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: Aceglatone(CAS DataBase Reference)
    11. NIST Chemistry Reference: Aceglatone(642-83-1)
    12. EPA Substance Registry System: Aceglatone(642-83-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 642-83-1(Hazardous Substances Data)

642-83-1 Usage

Uses

Used in Pharmaceutical Industry:
Aceglatone is used as an antihypertensive agent for its ability to lower blood pressure by inhibiting the angiotensin-converting enzyme, thus reducing the risk of cardiovascular diseases such as hypertension and heart failure.
Used in Cardiovascular Disease Management:
Aceglatone is used as a therapeutic agent for improving endothelial function and reducing inflammation, which can be beneficial for patients with conditions like diabetes and atherosclerosis.
Used in Research and Development:
Aceglatone is used as a subject of study for its potential applications in the treatment of cardiovascular and inflammatory diseases, with ongoing research exploring its efficacy and safety in clinical settings.

Check Digit Verification of cas no

The CAS Registry Mumber 642-83-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 642-83:
(5*6)+(4*4)+(3*2)+(2*8)+(1*3)=71
71 % 10 = 1
So 642-83-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H10O8/c1-3(11)15-7-5-6(18-9(7)13)8(10(14)17-5)16-4(2)12/h5-8H,1-2H3/t5-,6-,7-,8+/m1/s1

642-83-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Aceglatone

1.2 Other means of identification

Product number -
Other names 2,5-Di-O-acetyl-D-glucosaccharo-1,4-3,6-dilacton

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:642-83-1 SDS

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